Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.44 |
| ▸ | EED | O75530 | 10/20 | 0.44 |
| ▸ | RBBP4 | Q09028 | 10/20 | 0.44 |
| ▸ | SUZ12 | Q15022 | 10/20 | 0.44 |
| ▸ | AEBP2 | Q6ZN18 | 8/20 | 0.44 |
| ▸ | RBBP7 | Q16576 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2594971 | 0.81 | EZH2 (0.63) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL2593248 | 0.77 | EZH2 (0.60) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL2596024 | 0.72 | EZH2 (0.68) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL2593765 | 0.70 | EZH2 (0.80) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL14717385 | 0.68 | EZH2 (0.71) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL19621028 | 0.68 | EZH2 (0.47) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL14718486 | 0.67 | EZH2 (0.63) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL2595042 | 0.66 | EZH2 (0.63) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL13468458 | 0.66 | EZH2 (0.74) | EZH2 | |
| SCHEMBL13468459 | 0.66 | EZH2 (0.71) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011140324-A1 | INDOLES | GLAXOSMITHKLINE LLC (US) | 2011-11-10 | — | — | WO | claimed |