Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI2 | P48307 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622597 | 1.00 | TFPI2 (0.54) | TFPI2KMT2AMEN1FABP4KDM4E | |
| SCHEMBL27887683 | 0.86 | TFPI2 (0.51) | TFPI2KMT2AMEN1FABP4KDM4E | |
| SCHEMBL887130 | 0.85 | CREBBP (0.55) | TFPI2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL14301382 | 0.84 | KMT2A (0.61) | TFPI2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL18856031 | 0.83 | TFPI2 (0.49) | TFPI2KMT2AMEN1FABP4KDM4E | |
| SCHEMBL8530590 | 0.83 | TFPI2 (0.49) | TFPI2KMT2AMEN1FABP4KDM4E | |
| SCHEMBL8076273 | 0.80 | KMT2A (0.67) | TFPI2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL8528870 | 0.80 | TFPI2 (0.47) | TFPI2KMT2AMEN1FABP4KDM4E | |
| SCHEMBL28477612 | 0.80 | TFPI2 (0.47) | TFPI2KMT2AMEN1FABP4KDM4E | |
| SCHEMBL25446125 | 0.79 | TFPI2 (0.46) | TFPI2KMT2AMEN1FABP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143911-B | Preparation method of N- (indole-N-formyl) -alpha-amino amide derivative | 浙江大学 | 2021-12-17 | — | — | CN | claimed |
| CN-110143911-B | Preparation method of N- (indole-N-formyl) -alpha-amino amide derivative | 浙江大学 | 2021-12-17 | — | — | CN | disclosed |
| EP-2566327-A1 | INDOLES | GlaxoSmithKline LLC (US) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011140324-A1 | INDOLES | GLAXOSMITHKLINE LLC (US) | 2011-11-10 | — | — | WO | disclosed |
| EP-2102204-B1 | NEW AMINOPYRROLO[1,2- A]INDOLE ET AMINOPYRIDAZINO[1,6-A]INDOLE DERIVATIVES, METHOD FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | SERVIER LAB (FR) | 2010-05-05 | — | — | EP | disclosed |
| EP-2102204-A1 | NEW AMINOPYRROLO[1,2- A]INDOLE ET AMINOPYRIDAZINO[1,6-A]INDOLE DERIVATIVES, METHOD FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Les Laboratoires Servier (FR) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008099082-A1 | NEW AMINOPYRROLO[1,2-Α]INDOLE ET AMINOPYRIDAZINO[1,6-Α]INDOLE DERIVATIVES, METHOD FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | LES LABORATOIRES SERVIER (FR) | 2008-08-21 | — | — | WO | disclosed |
| CN-1972930-A | Novel pyridazinone derivatives as inhibitors of CDK2 | AVENTIS PHARMA SA (FR) | 2007-05-30 | — | — | CN | disclosed |
| EP-1549309-A4 | SOMATOSTATIN ANALOGUE COMPOUNDS | CHEMBRIDGE RES LAB INC (US) | 2006-05-17 | — | — | EP | disclosed |
| EP-1549309-A2 | SOMATOSTATIN ANALOGUE COMPOUNDS | ChemBridge Research Laboratories, Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| US-6872827-B2 | Somatostatin analogue compounds | CHEMBRIDGE RESEARCH LABORATORIES, INC. (US) | 2005-03-29 | — | — | US | disclosed |
| US-20040019069-A1 | Somatostatin analogue compounds | CHEMBRIDGE CORPORATION | 2004-01-29 | — | — | US | disclosed |
| WO-2003090677-A2 | SOMATOSTATIN ANALOGUE COMPOUNDS | CHEMBRIDGE RESEARCH LAB., LLC (US) | 2003-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019069-A1 | Somatostatin analogue compounds | SSTR2, SSTR1, SSTR4 | TFPI2 3792/4885KMT2A 1844/4885MEN1 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.