Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 19/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25330069 | 0.91 | TOP1 (0.58) | TOP1MEN1KMT2A | |
| SCHEMBL25938820 | 0.89 | TOP1 (0.54) | TOP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL25330940 | 0.89 | TOP1 (0.53) | TOP1MEN1KMT2A | |
| SCHEMBL25954261 | 0.85 | TOP1 (0.62) | TOP1MEN1KMT2A | |
| SCHEMBL9559833 | 0.84 | TOP1 (0.73) | TOP1MEN1KMT2A | |
| SCHEMBL30409333 | 0.83 | TOP1 (0.67) | TOP1MEN1KMT2A | |
| SCHEMBL23963966 | 0.83 | TOP1 (0.65) | TOP1MEN1KMT2A | |
| SCHEMBL25329300 | 0.83 | TOP1 (0.66) | TOP1MEN1KMT2A | |
| SCHEMBL31421876 | 0.83 | TOP1 (0.66) | TOP1MEN1KMT2A | |
| SCHEMBL23963998 | 0.83 | TOP1 (0.74) | TOP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | CD4, DCLRE1A, TOP1 | TOP1 3/4885MEN1 188/4885KMT2A 2544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.