⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21672697 | 0.76 | GRM5 (0.35) | — | |
| SCHEMBL13455921 | 0.73 | — | — | |
| SCHEMBL13455832 | 0.72 | PDCD1 (0.44) | — | |
| SCHEMBL16327989 | 0.69 | — | — | |
| SCHEMBL24346205 | 0.69 | — | — | |
| SCHEMBL12655097 | 0.66 | — | — | |
| SCHEMBL21334985 | 0.65 | MAP4K1 (0.39) | — | |
| SCHEMBL22503002 | 0.64 | CDC7 (0.31) | — | |
| SCHEMBL18183947 | 0.63 | PDE4B (0.32) | — | |
| SCHEMBL26890600 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555070-B1 | AMINE-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS AND METHODS OF USE THEREOF | EPIZYME INC (US) | 2023-08-09 | — | — | EP | disclosed |