Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25890305 | 0.83 | ACKR3 (0.32) | DRD4 | |
| SCHEMBL23323491 | 0.80 | DRD4 (0.31) | DRD4 | |
| SCHEMBL23338582 | 0.79 | BCHE (0.31) | BCHE | |
| SCHEMBL23324916 | 0.78 | BCHE (0.38) | BCHEDPP4 | |
| SCHEMBL25905689 | 0.77 | SSTR4 (0.36) | BCHE | |
| SCHEMBL13444989 | 0.73 | TDP1 (0.45) | BCHEDPP4 | |
| SCHEMBL25909029 | 0.70 | HRH3 (0.34) | — | |
| SCHEMBL2737211 | 0.68 | HRH3 (0.43) | DPP4 | |
| SCHEMBL25932655 | 0.68 | SMN1; SMN2 (0.42) | DPP4 | |
| SCHEMBL29303016 | 0.67 | ATM (0.33) | BCHEDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | KRAS, HRAS, MTOR | BCHE 3850/4885DPP4 3661/4885DRD4 4733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.