⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24006755 | 0.78 | — | — | |
| SCHEMBL19046064 | 0.76 | — | — | |
| SCHEMBL24007186 | 0.74 | — | — | |
| SCHEMBL24007185 | 0.69 | — | — | |
| SCHEMBL24007197 | 0.67 | — | — | |
| SCHEMBL25078508 | 0.66 | — | — | |
| SCHEMBL23939693 | 0.66 | PTPN1 (0.32) | — | |
| SCHEMBL16090746 | 0.66 | — | — | |
| SCHEMBL15047185 | 0.66 | — | — | |
| SCHEMBL23131186 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223317-A2 | MODULATION OF COMPLEMENT ACTIVITY | RA Pharmaceuticals, Inc. (US) | 2023-08-09 | — | — | EP | disclosed |