Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | GPR142 | Q7Z601 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25340004 | 0.82 | PDE10A (0.40) | PDE10AKCNH2SCN9ASCN1ASCN4A | |
| SCHEMBL25952094 | 0.71 | PDE10A (0.40) | PDE10AKCNH2SCN9ASCN1ASCN4A | |
| SCHEMBL30544023 | 0.70 | PDE10A (0.48) | PDE10ASCN9A | |
| SCHEMBL25952769 | 0.70 | PDE10A (0.48) | PDE10ASCN9A | |
| SCHEMBL25338851 | 0.69 | TRPV1 (0.50) | PDE10AFEN1 | |
| SCHEMBL30543994 | 0.69 | SCN9A (0.35) | PDE10AKCNH2SCN9ASCN1ASCN4A | |
| SCHEMBL25955647 | 0.69 | PDE10A (0.40) | PDE10AFEN1 | |
| SCHEMBL20394471 | 0.68 | CREBBP (0.40) | ALDH1A1MAPTATM | |
| SCHEMBL25973899 | 0.68 | FEN1 (0.51) | PDE10AFEN1 | |
| SCHEMBL20394349 | 0.68 | SCN9A (0.46) | PDE10ASCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |