Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 6/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL8927677 | 1.00 | FFAR3 (0.62) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Propionic Acid SCHEMBL8342622 | 1.00 | FFAR3 (0.62) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Propionic Acid SCHEMBL1326488 | 1.00 | FFAR3 (0.62) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Propionic Acid SCHEMBL235022 | 1.00 | FFAR3 (0.62) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Propionic Acid SCHEMBL11588668 | 0.94 | FFAR3 (0.56) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Propionic Acid SCHEMBL28034572 | 0.88 | FFAR3 (0.56) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Propionic Acid SCHEMBL28193865 | 0.88 | FFAR3 (0.56) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Propionic Acid SCHEMBL30166958 | 0.88 | FFAR3 (0.56) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butyric Acid SCHEMBL8863585 | 0.87 | FFAR3 (0.62) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Propionic Acid SCHEMBL28129215 | 0.87 | FFAR3 (0.48) | FFAR3HDAC1HDAC2HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108715749-B | High-ultraviolet-resistance waterproof adhesive and preparation method thereof | 嘉好(太仓)新材料股份有限公司 | 2020-07-14 | — | — | CN | claimed |
| CN-119125335-A | In-vivo analysis method of polyorthoester and application thereof | 广东药科大学 | 2024-12-13 | — | — | CN | disclosed |
| CN-112176722-A | Poly (p-phenylene benzobisoxazole) fiber spinning oil and preparation method thereof | 天津工业大学 | 2021-01-05 | — | — | CN | disclosed |
| US-9149426-B2 | Nanoparticle composition and methods to make and use the same | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2015-10-06 | — | — | US | disclosed |
| US-20130209566-A1 | NANOPARTICLE COMPOSITION AND METHODS TO MAKE AND USE THE SAME | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2013-08-15 | — | — | US | disclosed |
| US-20120149864-A1 | POLY(ORTHOESTER) POLYMERS, AND METHODS OF MAKING AND USING SAME | MEDTRONICS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-8133968-B2 | Poly(orthoester) polymers, and methods of making and using same | MEDTRONIC, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-20110082275-A1 | POLY(ORTHOESTER) POLYMERS, AND METHODS OF MAKING AND USING SAME | MEDTRONIC, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| US-7875697-B2 | Poly(orthoester) polymers, and methods of making and using same | MEDTRONIC, INC. (US) | 2011-01-25 | — | — | US | disclosed |
| EP-2044142-A2 | POLY(ORTHOESTER) POLYMERS, AND METHODS OF MAKING AND USING SAME | Medtronic, Inc. (US) | 2009-04-08 | — | — | EP | disclosed |
| US-20080033140-A1 | Poly(orthoester) polymers, and methods of making and using same | MEDTRONIC, INC. | 2008-02-07 | — | — | US | disclosed |
| WO-2008005371-A2 | POLY(ORTHOESTER) POLYMERS, AND METHODS OF MAKING AND USING SAME | MEDTRONIC, INC. (US) | 2008-01-10 | — | — | WO | disclosed |
| CN-101072802-A | Hydrophobically modified cationic polymers and their use as cleaning aids | CIBA SC HOLDING AG (CH) | 2007-11-14 | — | — | CN | disclosed |
| US-5661181-A | Non-cyclic esters for pest control | CORNELL RESEARCH FOUNDATION, INC. (US) | 1997-08-26 | — | — | US | disclosed |
| WO-1993015767-A1 | IMPLANT THERAPY FOR BONE GROWTH STIMULATION | MERCK & CO., INC. (US) | 1993-08-19 | — | — | WO | disclosed |
| US-5217712-A | Controlled drug delivery, prosthetic tissues | MERCK & CO., INC. (US) | 1993-06-08 | — | — | US | disclosed |
| US-5047464-A | Crosslinked polyorthoesters; drug deliver; resilience | MERCK & CO., INC. (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0419156-A2 | Bioerodible thermoset elastomers | MERCK & CO. INC. (US) | 1991-03-27 | — | — | EP | disclosed |
| US-4275174-A | METHYL METHACRYLATE-STYRENE COPOLYMER FORMED IN THE PRESENCE OF A POLYOL BORIC ACID ESTER | KYOWA GAS CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-06-23 | — | — | US | disclosed |