Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2630783 | 0.84 | PDE10A (0.57) | PDE10APDE2A | |
| SCHEMBL2590418 | 0.81 | PDE10A (0.67) | PDE10A | |
| Hydrochloric Acid SCHEMBL16454574 | 0.80 | PDE10A (0.65) | PDE10A | |
| SCHEMBL2595706 | 0.75 | PDE10A (1.00) | PDE10A | |
| SCHEMBL17679988 | 0.74 | PDE10A (0.80) | PDE10A | |
| SCHEMBL9989113 | 0.72 | PDE10A (0.82) | PDE10A | |
| SCHEMBL2595779 | 0.72 | PDE10A (1.00) | PDE10APDE2A | |
| SCHEMBL2590281 | 0.71 | PDE10A (0.81) | PDE10A | |
| SCHEMBL2595763 | 0.71 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2596168 | 0.71 | PDE10A (1.00) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569300-A1 | NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS | Amgen Inc. (US) | 2013-03-20 | — | — | EP | claimed |
| WO-2011143365-A1 | NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS | AMGEN INC. (US) | 2011-11-17 | — | — | WO | claimed |