⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23338573 | 0.77 | SOS1 (0.46) | — | |
| SCHEMBL25124976 | 0.68 | SOS1 (0.46) | — | |
| SCHEMBL21945578 | 0.68 | SOS1 (0.46) | — | |
| SCHEMBL24720256 | 0.68 | SOS1 (0.39) | — | |
| SCHEMBL27443832 | 0.66 | SOS1 (0.52) | — | |
| SCHEMBL21210664 | 0.64 | SOS1 (0.48) | — | |
| SCHEMBL24568091 | 0.63 | SOS1 (0.41) | — | |
| SCHEMBL17789639 | 0.63 | SOS1 (0.45) | — | |
| SCHEMBL22989400 | 0.62 | SOS1 (0.34) | — | |
| SCHEMBL25785225 | 0.61 | SOS1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |