SCHEMBL25959653

SCHEMBL25959653

CCOCc1nc2c(N)nc3cccc4c3c2n1CCCO4

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.47
TLR8 Q9NR97 11/20 0.47
NUDT1 P36639 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21730950 0.94 TLR7 (0.46) TLR7TLR8NUDT1
SCHEMBL21712426 0.82 TLR7 (0.43) TLR7TLR8NUDT1
SCHEMBL21712385 0.82 TLR7 (0.45) TLR7TLR8NUDT1
SCHEMBL21712367 0.82 TLR7 (0.45) TLR7TLR8NUDT1
SCHEMBL25959643 0.82 TLR7 (0.45) TLR7TLR8NUDT1
SCHEMBL25960847 0.81 TLR7 (0.45) TLR7TLR8NUDT1
SCHEMBL25959636 0.81 TLR7 (0.45) TLR7TLR8NUDT1
SCHEMBL21712293 0.81 TLR7 (0.45) TLR7TLR8NUDT1
SCHEMBL21712383 0.81 TLR7 (0.45) TLR7TLR8NUDT1
SCHEMBL25959327 0.79 TLR7 (0.40) TLR7TLR8NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3615539-B1 2-AMINO-QUINOLINE DERIVATIVES BIRDIE BIOPHARMACEUTICALS INC (KY) 2023-08-09 EP disclosed