Benzo[D]Oxazole

Benzo[D]Oxazole

SCHEMBL2595997

[PoH2].c1ccc2ocnc2c1

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
CTNNB1 P35222 4/20 0.42
WNT3A P56704 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
MAPT P10636 4/20 0.41
DYRK1A Q13627 2/20 0.40
ALDH1A1 P00352 4/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
GAA P10253 2/20 0.39
ELANE P08246 1/20 0.38
GPR3 P46089 2/20 0.36
KDM4E B2RXH2 4/20 0.35
HPGD P15428 3/20 0.35
HSD17B10 Q99714 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
POLB P06746 1/20 0.35
PKM P14618 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[D]Oxazole SCHEMBL2385440 0.97 NPC1 (0.43) NPC1RAB9ACTNNB1WNT3ASMN1; SMN2
Benzo[D]Oxazole SCHEMBL7903 0.97
Benzo[D]Oxazole SCHEMBL2724328 0.97
Benzo[D]Oxazole SCHEMBL27844655 0.97 NPC1 (0.43) NPC1RAB9ACTNNB1WNT3ASMN1; SMN2
Benzo[D]Oxazole SCHEMBL5383185 0.95 NPC1 (0.42) NPC1RAB9ACTNNB1WNT3ASMN1; SMN2
Benzo[D]Oxazole SCHEMBL11738771 0.95 NPC1 (0.42) NPC1RAB9ACTNNB1WNT3ASMN1; SMN2
Benzo[D]Oxazole SCHEMBL17822109 0.95 NPC1 (0.42) NPC1RAB9ACTNNB1WNT3ASMN1; SMN2
Benzo[D]Oxazole SCHEMBL4560878 0.95 NPC1 (0.42) NPC1RAB9ACTNNB1WNT3ASMN1; SMN2
Benzo[D]Oxazole SCHEMBL21684956 0.95 NPC1 (0.42) NPC1RAB9ACTNNB1WNT3ASMN1; SMN2
Benzo[D]Oxazole SCHEMBL9499083 0.95 NPC1 (0.42) NPC1RAB9ACTNNB1WNT3ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6235436-B1 BLEND OF POLYBENZOXAZOLE, PHENOLIC RESIN AND POLYAMIDE; PREBAKING, EXPOSURE, DEVELOPMENT, HEAT CURING SUMITOMO BAKELITE COMPANY LIMITED (JP) 2001-05-22 US claimed
US-8926733-B2 Polymers, polymer membranes and methods of producing the same AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-01-06 US disclosed
EP-2569081-A1 POLYMERS, POLYMER MEMBRANES AND METHODS OF PRODUCING THE SAME Air Products and Chemicals, Inc. (US) 2013-03-20 EP disclosed
US-20130047844-A1 POLYMERS, POLYMER MEMBRANES AND METHODS OF PRODUCING THE SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-02-28 US disclosed
WO-2011143530-A1 POLYMERS, POLYMER MEMBRANES AND METHODS OF PRODUCING THE SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2011-11-17 WO disclosed
US-5273823-A Granules of compression moldable polybenzazole blocks and thermoplastic blocks THE DOW CHEMICAL COMPANY (US) 1993-12-28 US disclosed