Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 14/20 | 0.52 |
| ▸ | PLG | P00747 | 6/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25963630 | 0.92 | FOLH1 (0.52) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL25963776 | 0.91 | FOLH1 (0.60) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL25963614 | 0.89 | FOLH1 (0.53) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL30309112 | 0.88 | FOLH1 (0.57) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL25963639 | 0.86 | FOLH1 (0.46) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL25963648 | 0.85 | FOLH1 (0.67) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL29679197 | 0.84 | PLG (0.68) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL29679138 | 0.84 | FOLH1 (0.60) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL29679118 | 0.84 | FOLH1 (0.64) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL29679159 | 0.84 | FOLH1 (0.62) | FOLH1PLGPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230201383-A1 | PSMA TARGETING UREA-BASED LIGANDS FOR PROSTATE CANCER RADIOTHERAPY AND IMAGING | RIGSHOSPITALET (DK) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230201383-A1 | PSMA TARGETING UREA-BASED LIGANDS FOR PROSTATE CANCER RADIOTHERAPY AND IMAGING | KLK3, FOLH1, PSMA7 | FOLH1 2/4885PLG 990/4885PRSS1 351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.