⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24211177 | 0.81 | — | — | |
| SCHEMBL26342705 | 0.80 | MAPT (0.39) | — | |
| SCHEMBL20228108 | 0.77 | HSD17B10 (0.31) | — | |
| SCHEMBL18544367 | 0.75 | HSD17B10 (0.30) | — | |
| SCHEMBL25962994 | 0.74 | — | — | |
| SCHEMBL20067718 | 0.71 | — | — | |
| SCHEMBL19704121 | 0.71 | — | — | |
| SCHEMBL12243875 | 0.64 | MEN1 (0.36) | — | |
| SCHEMBL20997017 | 0.64 | MAPT (0.36) | — | |
| SCHEMBL26273991 | 0.64 | MAPT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372511-A1 | ANTIBODY-IMMUNE AGONIST CONJUGATE AND APPLICATIONS THEREOF | GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
| US-11717576-B2 | Antibody-immune agonist conjugate and applications thereof | GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) | 2023-08-08 | — | — | US | disclosed |