Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.42 |
| ▸ | CA2 | P00918 | 8/20 | 0.42 |
| ▸ | CA9 | Q16790 | 6/20 | 0.42 |
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16010092 | 1.00 | CA1 (0.42) | CA1CA2CA9CA12TSHR | |
| SCHEMBL14885478 | 1.00 | CA1 (0.42) | CA1CA2CA9CA12TSHR | |
| SCHEMBL14882300 | 1.00 | CA1 (0.42) | CA1CA2CA9CA12TSHR | |
| SCHEMBL23380322 | 0.84 | KDM1A (0.39) | TSHRALDH1A1GAAKDM1ALMNA | |
| SCHEMBL30335078 | 0.84 | KDM1A (0.39) | TSHRALDH1A1GAAKDM1ALMNA | |
| SCHEMBL29879981 | 0.83 | KMT2A (0.40) | CA1CA2CA9CA12TSHR | |
| SCHEMBL24738876 | 0.83 | KMT2A (0.40) | CA1CA2CA9CA12TSHR | |
| SCHEMBL14709116 | 0.83 | KMT2A (0.40) | CA1CA2CA9CA12TSHR | |
| SCHEMBL10679335 | 0.81 | CA1 (0.36) | CA1CA2CA9CA12TSHR | |
| SCHEMBL28856480 | 0.80 | CA1 (0.43) | CA1CA2CA9CA12TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495349-B1 | (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2023-06-28 | — | — | EP | disclosed |