Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25965310 | 0.97 | KDM4E (0.35) | KDM4EATML3MBTL1BACE1 | |
| SCHEMBL25964983 | 0.97 | KDM4E (0.36) | KDM4EATML3MBTL1BACE1PTGER4 | |
| SCHEMBL25965027 | 0.97 | KDM4E (0.38) | KDM4EATML3MBTL1BACE1PTGER4 | |
| SCHEMBL25964990 | 0.96 | KDM4E (0.35) | KDM4EATML3MBTL1BACE1 | |
| SCHEMBL23299592 | 0.95 | KDM4E (0.38) | KDM4EATML3MBTL1BACE1PTGER4 | |
| SCHEMBL25964902 | 0.94 | KDM4E (0.35) | KDM4EATML3MBTL1BACE1PTGER4 | |
| SCHEMBL25965354 | 0.94 | KDM4E (0.35) | KDM4EATML3MBTL1BACE1 | |
| SCHEMBL25965025 | 0.94 | KDM4E (0.37) | KDM4EATML3MBTL1BACE1PTGER4 | |
| SCHEMBL25965308 | 0.93 | KDM4E (0.35) | KDM4EATML3MBTL1BACE1TP53 | |
| SCHEMBL25964903 | 0.93 | KDM4E (0.35) | KDM4EATML3MBTL1BACE1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230255106-A1 | ORGANIC ELECTROLUMINESCENT APPARATUS | MERCK PATENT GMBH (DE) | 2023-08-10 | — | — | US | disclosed |
| US-20230255106-A1 | ORGANIC ELECTROLUMINESCENT APPARATUS | MERCK PATENT GMBH (DE) | 2023-08-10 | — | — | US | disclosed |