Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25457857 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2HPGDNPC1RAB9ACYP1A2 | |
| SCHEMBL21152897 | 0.80 | APP (0.41) | SMN1; SMN2HPGDRAB9AKDM4EMEN1 | |
| SCHEMBL5023024 | 0.80 | HPGD (0.65) | SMN1; SMN2HPGDNPC1RAB9ACYP1A2 | |
| SCHEMBL15143918 | 0.79 | SMN1; SMN2 (0.79) | SMN1; SMN2HPGDNPC1RAB9ACYP1A2 | |
| SCHEMBL9674322 | 0.77 | SMN1; SMN2 (0.61) | SMN1; SMN2HPGDNPC1RAB9ACYP1A2 | |
| SCHEMBL8867553 | 0.76 | CYP4F2 (0.59) | SMN1; SMN2HPGDNPC1RAB9ACYP1A2 | |
| SCHEMBL8867545 | 0.76 | NPC1 (0.59) | SMN1; SMN2HPGDNPC1RAB9ACYP1A2 | |
| SCHEMBL14349998 | 0.76 | HPGD (0.59) | SMN1; SMN2HPGDNPC1RAB9ACYP1A2 | |
| SCHEMBL22625788 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDNPC1RAB9ACYP1A2 | |
| SCHEMBL22001309 | 0.75 | MEN1 (0.56) | SMN1; SMN2RAB9ACYP1A2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230256109-A1 | Trans-Cyclooctene Bioorthogonal Agents and Uses in Cancer and Immunotherapy | TAMBO, INC. | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230256109-A1 | Trans-Cyclooctene Bioorthogonal Agents and Uses in Cancer and Immunotherapy | ICOS, CD74, PBK | SMN1; SMN2 4078/4885HPGD 582/4885NPC1 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.