SCHEMBL25965301

SCHEMBL25965301

c1ccc(-c2cccc3oc4cc(-c5nc(-n6c7ccccc7c7ccccc76)nc(-n6c7ccccc7c7c8c(ccc76)-c6ccccc6C86c7ccccc7-c7ccccc76)n5)ccc4c23)cc1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25964975 0.96 BACE1 (0.33) BACE1
SCHEMBL25965839 0.93 AHR (0.32)
SCHEMBL25965335 0.91 BACE1 (0.31) BACE1
SCHEMBL25964714 0.91 AHR (0.30)
SCHEMBL25965411 0.90 AHR (0.30)
SCHEMBL25973888 0.90
SCHEMBL25965303 0.90
SCHEMBL25965019 0.88 BACE1 (0.31) BACE1
SCHEMBL25964533 0.87 BACE1 (0.31) BACE1
SCHEMBL27336392 0.87 BACE1 (0.36) BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed