Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 2/20 | 0.39 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21508113 | 0.82 | SLC22A2 (0.52) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL19484821 | 0.79 | SLC22A2 (0.33) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL19484612 | 0.79 | SLC22A2 (0.33) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL19484691 | 0.76 | SLC22A2 (0.31) | SLC22A2SLC47A1MAPTKMT2A | |
| SCHEMBL23911765 | 0.74 | SLC22A2 (0.48) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL19605667 | 0.71 | GRIN2D (0.47) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL25698824 | 0.71 | SLC22A2 (0.35) | SLC22A2SLC47A1MAPTKMT2A | |
| SCHEMBL21075180 | 0.70 | MEN1 (0.35) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL19495143 | 0.70 | GRIN2D (0.35) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL12530342 | 0.70 | GRIN2D (0.46) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11723980-B2 | IRAK degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11723980-B2 | IRAK degraders and uses thereof | IRAK2, IRAK3, IRAK1 | SLC22A2 4823/4885SLC47A1 4628/4885MAPT 2459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.