Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.71 |
| ▸ | PDCD1LG2 | Q9BQ51 | 18/20 | 0.71 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24613772 | 1.00 | CD274 (0.71) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL24613690 | 0.91 | CD274 (0.82) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL24613385 | 0.91 | CD274 (0.82) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL23948832 | 0.91 | CD274 (0.82) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL23961391 | 0.90 | CD274 (0.69) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL24613436 | 0.90 | CD274 (0.69) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL24613845 | 0.89 | CD274 (0.65) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL25967162 | 0.89 | CD274 (0.65) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL23961475 | 0.88 | CD274 (0.60) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL23961418 | 0.88 | CD274 (0.60) | CD274PDCD1LG2PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234030-A2 | PD-1/PD-L1 INHIBITORS | Gilead Sciences, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| EP-3820572-B1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES INC (US) | 2023-08-16 | — | — | EP | disclosed |