SCHEMBL25965848

SCHEMBL25965848

c1ccc(-n2c3ccccc3c3cc4c5ccccc5n(-c5cccc(-c6nc(-c7ccc8c(c7)oc7ccccc78)nc(-n7c8ccccc8c8ccccc87)n6)c5)c4cc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
AHR P35869 1/20 0.32
PTGER4 P35408 2/20 0.32
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
HCRTR1 O43613 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MMP12 P39900 1/20 0.31
MMP13 P45452 1/20 0.31
TTR P02766 1/20 0.30
IL1R1 P14778 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25965886 0.97 KDM4E (0.39) KDM4EATML3MBTL1AHRPTGER4
SCHEMBL25964934 0.96 ATM (0.35) KDM4EATML3MBTL1PTGER4HCRTR1
SCHEMBL19769736 0.96 KDM4E (0.40) KDM4EATML3MBTL1AHRPTGER4
SCHEMBL24216733 0.96 KDM4E (0.40) KDM4EATML3MBTL1AHRPTGER4
SCHEMBL19769739 0.95 ATM (0.38) KDM4EATML3MBTL1AHRPTGER4
SCHEMBL25965425 0.95 KDM4E (0.39) KDM4EATML3MBTL1AHRPTGER4
SCHEMBL22049395 0.95 KDM4E (0.39) KDM4EATML3MBTL1AHRPTGER4
SCHEMBL25965373 0.94 ATM (0.38) KDM4EATML3MBTL1AHRPTGER4
SCHEMBL25965850 0.94 KDM4E (0.40) KDM4EATML3MBTL1AHRPTGER4
SCHEMBL25965852 0.93 KDM4E (0.42) KDM4EATML3MBTL1AHRPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed