SCHEMBL25965883

SCHEMBL25965883

c1ccc(-n2c3ccccc3c3ccc4c(c5ccccc5n4-c4nc(-c5ccc6c(c5)oc5ccccc56)nc(-n5c6ccccc6c6ccccc65)n4)c32)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.33
LMNA P02545 1/20 0.33
AHR P35869 1/20 0.32
CA12 O43570 2/20 0.32
CA9 Q16790 2/20 0.32
ALDH1A1 P00352 3/20 0.32
PTGER4 P35408 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
NPSR1 Q6W5P4 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
HCRTR1 O43613 1/20 0.31
POLB P06746 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24800909 0.98 KDM4E (0.35) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL24078755 0.97 KDM4E (0.38) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL19769905 0.96 KDM4E (0.34) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL25965896 0.95 KDM4E (0.36) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL19769906 0.95 KDM4E (0.33) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL24078494 0.95 KDM4E (0.36) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL24802401 0.95 KDM4E (0.36) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL26055258 0.94 PTGER4 (0.32) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL23602246 0.94 KDM4E (0.38) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL25965873 0.93 KDM4E (0.35) KDM4EATML3MBTL1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed