SCHEMBL25966176

SCHEMBL25966176

c1ccc(-c2ccc(-c3cc(-c4ccccc4)nc(-c4cccc(-n5c6ccccc6c6ccc7c(c8ccccc8n7-c7ccccc7)c65)c4)n3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KMT2A Q03164 6/20 0.36
MEN1 O00255 5/20 0.36
ALDH1A1 P00352 3/20 0.36
MAPT P10636 3/20 0.36
HPGD P15428 3/20 0.36
LMNA P02545 2/20 0.36
NTSR1 P30989 1/20 0.35
GLA P06280 1/20 0.34
GAA P10253 1/20 0.33
PTGER4 P35408 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
DHODH Q02127 1/20 0.32
HDAC4 P56524 1/20 0.31
IL1R1 P14778 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22596582 1.00 KDM4E (0.40) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL22596129 0.99 KDM4E (0.39) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL12691168 0.98 KDM4E (0.42) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL12690808 0.98 KDM4E (0.42) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL17809395 0.97 KDM4E (0.38) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL22596196 0.97 KDM4E (0.39) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL22596413 0.97 KDM4E (0.38) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL22596383 0.97 KDM4E (0.38) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL22596581 0.96 KDM4E (0.38) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL21018158 0.96 KDM4E (0.38) KDM4EATML3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed