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SCHEMBL25966333

SCHEMBL25966333

CC1(C)c2ccccc2-c2ccc3c4ccccc4n(-c4cccc(-c5nc(-c6ccccc6)nc(-n6c7ccccc7c7ccccc76)n5)c4)c3c21

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ DUSP3 P51452 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30
▸ ATM Q13315 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30
▸ ABCG2 Q9UNQ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25965972 0.98 DUSP3 (0.31) DUSP3
SCHEMBL31719 0.97 DUSP3 (0.33) DUSP3KDM4EATML3MBTL1ABCG2
SCHEMBL24078784 0.96 KDM4E (0.33) DUSP3HSD17B10KDM4EATML3MBTL1
SCHEMBL25966421 0.96 KDM4E (0.34) DUSP3KDM4EATML3MBTL1ABCG2
SCHEMBL18505566 0.95 DUSP3 (0.32) DUSP3KDM4EATML3MBTL1
SCHEMBL18564355 0.95 DUSP3 (0.34) DUSP3KDM4EATML3MBTL1
SCHEMBL25966524 0.94 KDM4E (0.32) DUSP3KDM4EATML3MBTL1
SCHEMBL19104575 0.94 PDE10A (0.33) DUSP3KDM4EATML3MBTL1
SCHEMBL24078570 0.94 KDM4E (0.33) DUSP3KDM4EATML3MBTL1
SCHEMBL25628590 0.93 DUSP3 (0.31) DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 — — US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 — — US disclosed
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