Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | PARP1 | P09874 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.49 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25970991 | 0.90 | PARP1 (0.60) | TSHRPARP1KMT2AALDH1A1MAOA | |
| SCHEMBL14073116 | 0.82 | PARP1 (0.62) | TSHRPARP1KMT2AALDH1A1MAOA | |
| SCHEMBL14072985 | 0.81 | TSHR (0.85) | TSHRPARP1ALDH1A1MAOAMAPT | |
| SCHEMBL14073166 | 0.81 | PARP1 (0.57) | TSHRPARP1KMT2AALDH1A1MAOA | |
| SCHEMBL8191474 | 0.80 | PARP1 (0.71) | TSHRPARP1ALDH1A1MMP12NR3C2 | |
| SCHEMBL7276275 | 0.80 | PARP1 (0.56) | TSHRPARP1KMT2AALDH1A1MAOA | |
| SCHEMBL8196052 | 0.80 | TSHR (0.58) | TSHRPARP1KMT2AALDH1A1MAOA | |
| SCHEMBL14073044 | 0.79 | TSHR (0.73) | TSHRPARP1KMT2AALDH1A1HPGD | |
| SCHEMBL4129690 | 0.79 | TRPV1 (0.50) | — | |
| SCHEMBL14073033 | 0.79 | TSHR (0.76) | TSHRPARP1ALDH1A1MAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250088-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250088-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | TSHR 4477/4885PARP1 980/4885KMT2A 3713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.