Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 16/20 | 0.64 |
| ▸ | PTGES | O14684 | 5/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25968431 | 0.90 | PTGES2 (0.64) | PTGES2PTGESPTGS2PTGS1CYP1A2 | |
| SCHEMBL25968429 | 0.90 | PTGES2 (0.66) | PTGES2PTGESPTGS2PTGS1CYP1A2 | |
| SCHEMBL25968366 | 0.90 | PTGES2 (0.77) | PTGES2PTGESPTGS2PTGS1CYP1A2 | |
| SCHEMBL25968363 | 0.88 | PTGES2 (0.64) | PTGES2PTGESPTGS2PTGS1CYP1A2 | |
| SCHEMBL25968433 | 0.88 | PTGES2 (0.60) | PTGES2PTGESPTGS2PTGS1CYP1A2 | |
| SCHEMBL25968368 | 0.86 | PTGES2 (0.60) | PTGES2PTGESPTGS2PTGS1CYP1A2 | |
| SCHEMBL23270737 | 0.80 | PTGES2 (0.77) | PTGES2PTGESPTGS2PTGS1CYP1A2 | |
| SCHEMBL30181373 | 0.80 | PTGES2 (0.77) | PTGES2PTGESPTGS2PTGS1CYP1A2 | |
| SCHEMBL25968427 | 0.80 | PTGES2 (0.66) | PTGES2PTGESPTGS2PTGS1CYP1A2 | |
| SCHEMBL30770982 | 0.80 | PTGES2 (0.58) | PTGES2PTGESPTGS2PTGS1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718614-B2 | Compounds and methods for treatment of hedgehog pathway associated conditions | SUZHOU MEDNES PHARMA TECH CO., LTD. (CN) | 2023-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718614-B2 | Compounds and methods for treatment of hedgehog pathway associated conditions | SHH, GLI1, SMO | PTGES2 1332/4885PTGES 1603/4885PTGS2 646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.