⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29451611 | 1.00 | — | — | |
| SCHEMBL28602528 | 0.85 | — | — | |
| SCHEMBL31729551 | 0.81 | — | — | |
| SCHEMBL535618 | 0.81 | — | — | |
| Ammonia Solution, Strong SCHEMBL25341066 | 0.79 | UHRF1 (0.58) | — | |
| SCHEMBL29479539 | 0.77 | — | — | |
| SCHEMBL191846 | 0.77 | — | — | |
| SCHEMBL1644729 | 0.77 | — | — | |
| SCHEMBL30669490 | 0.77 | — | — | |
| SCHEMBL6307027 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580179-A | Preparation method of 2-chloro-4-cyclohexyl-5-methylpyridine | 上海鲲博玖瑞医药科技发展有限公司 | 2024-09-03 | — | — | CN | claimed |
| CN-117753351-A | Constant temperature and constant pressure preparation device for 2-chloro-4-amino-5-methylpyridine organic compound | 南京康德祥医药科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117069651-A | Continuous synthesis method of 2-chloro-4-amino-5-methylpyridine | 福建桦智工程技术有限公司 | 2023-11-17 | — | — | CN | claimed |
| CN-114957250-B | N- (9H-pyridine [2,3-b ] indol-4-yl) aryl carboxamide derivative and preparation method and application thereof | 中国人民解放军北部战区总医院 | 2023-05-09 | — | — | CN | claimed |
| CN-115991670-A | Preparation method of 4-bromo-6-chloronicotinic acid | 山西永津集团有限公司 | 2023-04-21 | — | — | CN | claimed |
| CN-115894354-A | Synthetic method of non-neferide ketone intermediate 4-amino-5-methylpyridine-2-alcohol | 中国药科大学 | 2023-04-04 | — | — | CN | claimed |
| CN-115340492-A | Preparation method of 2-hydroxy-4-amino-5-methylpyridine | 武汉海特生物创新医药研究有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-114957250-A | N- (9H-pyridine [2,3-b ] indole-4-yl) aryl formamide derivatives, and preparation method and application thereof | 中国人民解放军北部战区总医院 | 2022-08-30 | — | — | CN | claimed |
| CN-114656400-A | Preparation method of key intermediate of non-neferitone | 浙江科聚生物医药有限公司 | 2022-06-24 | — | — | CN | claimed |
| CN-103193704-A | 2-hydroxy-4-amino-5-methylpyridine heterocyclic compound | SICHUAN BERARE BIOLOG MEDICAL CO LTD | 2013-07-10 | — | — | CN | claimed |
| EP-4735431-A2 | MK2 INHIBITORS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2026-05-06 | — | — | EP | disclosed |
| US-12616696-B2 | Crystalline forms of (p)-3-chloro-4-((3,5-difluoropyridin-2-yl)methoxy)-2′-(2-(2-hydroxypropan-2-yl)pyrimidin-4-yl)-5′,6-dimethyl-2h-[1,4′-bipyridin]-2-one | ACLARIS THERAPEUTICS, INC. (US) | 2026-05-05 | — | — | US | disclosed |
| CN-117069651-B | Continuous synthesis method of 2-chloro-4-amino-5-methylpyridine | 福建桦智工程技术有限公司 | 2026-04-24 | — | — | CN | disclosed |
| CN-117069651-B | Continuous synthesis method of 2-chloro-4-amino-5-methylpyridine | 福建桦智工程技术有限公司 | 2026-04-24 | — | — | CN | disclosed |
| US-20260078122-A1 | INDAZOLE COMPOUNDS AS PKMYT1 KINASE INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2026-03-19 | — | — | US | disclosed |
| US-20050234059-A1 | Heterocyclic inhibitors of ERK2 and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED | 2005-10-20 | — | — | US | disclosed |
| EP-1506189-A1 | PYRROLE DERIVATIVES AS INHIBITORS OF ERK2 AND USES THEREOF | Vertex Pharmaceuticals Incorporated (US) | 2005-02-16 | — | — | EP | disclosed |
| US-20040029857-A1 | Heterocyclic inhibitors of ERK2 and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED | 2004-02-12 | — | — | US | disclosed |
| WO-2003091246-A1 | PYRROLE DERIVATIVES AS INHIBITORS OF ERK2 AND USES THEREOF | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2003-11-06 | — | — | WO | disclosed |
| CN-1311185-A | Method for preparing 4-amino pyridine and its derivatives | XINHUA PHARMACEUTICAL CO LTD S (CN) | 2001-09-05 | — | — | CN | disclosed |