Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.48 |
| ▸ | HPGD | P15428 | 8/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | GLA | P06280 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30516225 | 0.95 | KDM4E (0.56) | KDM4EHTTABCB1ALDH1A1HPGD | |
| SCHEMBL25969726 | 0.94 | KDM4E (0.61) | KDM4EHTTABCB1ALDH1A1HPGD | |
| SCHEMBL25969729 | 0.92 | KDM4E (0.66) | KDM4EHTTABCB1ALDH1A1HPGD | |
| SCHEMBL25338703 | 0.90 | KDM4E (0.60) | KDM4EHTTABCB1ALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL31579090 | 0.89 | KDM4E (0.56) | KDM4EHTTABCB1ALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL30516238 | 0.89 | KDM4E (0.56) | KDM4EHTTABCB1ALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL31579036 | 0.89 | KDM4E (0.56) | KDM4EHTTABCB1ALDH1A1HPGD | |
| SCHEMBL25969141 | 0.85 | KDM4E (0.77) | KDM4EHTTALDH1A1HPGDNPSR1 | |
| SCHEMBL25970068 | 0.84 | KDM4E (0.57) | KDM4EHTTALDH1A1HPGDNPSR1 | |
| SCHEMBL25969590 | 0.83 | PARP1 (0.51) | KDM4EHTTABCB1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141866-A1 | PYRAZOLOPYRIMIDINES AS MODULATORS OF SPERMINE OXIDASE | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-03 | — | — | WO | disclosed |