Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 16/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21997238 | 0.82 | PRKDC (0.45) | SMPD3PRKDCIRAK4 | |
| SCHEMBL26765837 | 0.82 | PRKDC (0.45) | SMPD3PRKDCIRAK4 | |
| SCHEMBL25971398 | 0.77 | SMPD3 (0.46) | SMPD3 | |
| SCHEMBL21997182 | 0.76 | IRAK4 (0.41) | SMPD3PRKDCIRAK4 | |
| SCHEMBL26765506 | 0.70 | IRAK4 (0.44) | SMPD3IRAK4 | |
| SCHEMBL26765718 | 0.70 | IRAK4 (0.44) | SMPD3IRAK4 | |
| SCHEMBL25339027 | 0.68 | SMPD3 (0.44) | SMPD3IRAK4 | |
| SCHEMBL25338794 | 0.68 | SMPD3 (0.44) | SMPD3IRAK4 | |
| SCHEMBL21998253 | 0.67 | PRKDC (0.42) | PRKDCPIK3CAACACB | |
| SCHEMBL21996887 | 0.67 | IRAK4 (0.43) | SMPD3IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147594-A2 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |