⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741527 | 0.92 | LCK (0.40) | — | |
| SCHEMBL2082092 | 0.83 | — | — | |
| SCHEMBL3875750 | 0.79 | — | — | |
| SCHEMBL7971596 | 0.79 | — | — | |
| SCHEMBL10568095 | 0.77 | LCK (0.35) | — | |
| SCHEMBL931024 | 0.77 | — | — | |
| SCHEMBL7616955 | 0.77 | — | — | |
| SCHEMBL736091 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL5555196 | 0.77 | LCK (0.56) | — | |
| SCHEMBL7616952 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256756-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA, INC. | 2014-09-11 | — | — | US | disclosed |
| US-8754226-B2 | Piperidinyl-substituted lactams as GPR119 modulators | ARRAY BIOPHARMA INC. (US) | 2014-06-17 | — | — | US | disclosed |
| US-20130158009-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA, INC. | 2013-06-20 | — | — | US | disclosed |
| WO-2013066869-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2013-05-10 | — | — | WO | disclosed |
| EP-2571864-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | Array Biopharma, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011146335-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2011-11-24 | — | — | WO | disclosed |
| US-5869024-A | USING A TRIODINATED PHENYL COMPOUND | BRACCO INTERNATIONAL B.V. (NL) | 1999-02-09 | — | — | US | disclosed |
| US-5628980-A | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. (NL) | 1997-05-13 | — | — | US | disclosed |
| US-5614638-A | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. (NL) | 1997-03-25 | — | — | US | disclosed |
| US-5591846-A | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. | 1997-01-07 | — | — | US | disclosed |
| US-5527926-A | TRIIODINATED PHENYL COMPOUNDS; ANTICOAGULANTS | BRACCO INTERNATIONAL B.V. (NL) | 1996-06-18 | — | — | US | disclosed |
| EP-0431838-B1 | Nonionic radiographic contrast agents | BRACCO INT BV (NL) | 1995-10-25 | — | — | EP | disclosed |
| CN-1107468-A | Preparation of novel heterocyclic nonionic contrast medium for radiophotograph | SQUIBB & SONS INC (US) | 1995-08-30 | — | — | CN | disclosed |
| US-5283243-A | Anti-inflammatory, anti-allergic, hypotensive and vasodilating agents | KALI-CHEMIE PHARMA GMBH (DE) | 1994-02-01 | — | — | US | disclosed |
| EP-0516050-A2 | Methods and compositions for using non-ionic contrast agents to reduce the risk of clot formation in diagnostic procedures | BRACCO INTERNATIONAL B.V. (NL) | 1992-12-02 | — | — | EP | disclosed |
| EP-0488009-A2 | Piperidinoalkyl-benzoxazine-and-thiazine-compounds, processes for their preparation and drugs containing them | Kali-Chemie Pharma GmbH (DE) | 1992-06-03 | — | — | EP | disclosed |
| EP-0431838-A1 | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. (NL) | 1991-06-12 | — | — | EP | disclosed |
| CN-1052114-A | Novel nonionic radiographic contrast agents | SQUIBB & SONS INC (US) | 1991-06-12 | — | — | CN | disclosed |