⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13884662 | 0.85 | — | — | |
| SCHEMBL28633047 | 0.81 | — | — | |
| SCHEMBL280557 | 0.81 | — | — | |
| SCHEMBL12073718 | 0.81 | — | — | |
| SCHEMBL19433170 | 0.81 | — | — | |
| SCHEMBL2455294 | 0.81 | — | — | |
| Isobutane SCHEMBL18094392 | 0.79 | S1PR2 (0.41) | — | |
| Butane SCHEMBL16739634 | 0.78 | KMT2A (0.40) | — | |
| SCHEMBL2685253 | 0.77 | HSP90AA1 (0.43) | — | |
| SCHEMBL29983622 | 0.77 | HSP90AA1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115322146-B | Preparation method of 4-amino-2, 6-dichloropyridine | 安徽峆一药业股份有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-114432900-B | Preparation method of anti-pollution composite reverse osmosis membrane and anti-pollution composite reverse osmosis membrane prepared by same | 沃顿科技股份有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-115322146-A | Preparation method of 4-amino-2,6-dichloropyridine | 安徽峆一药业股份有限公司 | 2022-11-11 | — | — | CN | claimed |
| CN-111960996-A | Preparation method of 4-amino-2, 6-dichloropyridine | 杭州珠联医药科技有限公司 | 2020-11-20 | — | — | CN | claimed |
| CN-107903246-A | A kind of sulfamide derivative, preparation method and its it is antitumor in application | 田立志 | 2018-04-13 | — | — | CN | claimed |
| CN-103145709-A | Synthesis process for 4-chloro-1,6-naphthyridine | SUZHOU KEJIE BIOLOG PHARMACEUTICAL CO LTD | 2013-06-12 | — | — | CN | claimed |
| US-20110312935-A1 | 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-12-22 | — | — | US | claimed |
| US-20110003790-A1 | PYRIDO [4, 3-D] PYRIMIDINONE DERIVATIVES AS KINASE INHIBITORS | IRM LLC (BM) | 2011-01-06 | — | — | US | claimed |
| EP-2250169-A1 | PYRIDO [4, 3-D]PYRIMIDINONE DERIVATIVES AS KINASE INHIBITORS | IRM LLC (BM) | 2010-11-17 | — | — | EP | claimed |
| US-20100234377-A1 | PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE | EVOTEC AG (DE) | 2010-09-16 | — | — | US | claimed |
| WO-2009099801-A1 | PYRIDO [4, 3-D] PYRIMIDINONE DERIVATIVES AS KINASE INHIBITORS | IRM LLC (BM) | 2009-08-13 | — | — | WO | claimed |
| EP-1802572-B1 | INDOL DERIVATIVES AS INHIBITORS OF SOLUBLE ADENYLYL CYCLASE | BAYER SCHERING PHARMA AG (DE) | 2009-04-22 | — | — | EP | claimed |
| JP-2008543917-A | — | — | 2008-12-04 | — | — | JP | claimed |
| WO-2008122787-A1 | PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE | EVOTEC AG (DE) | 2008-10-16 | — | — | WO | claimed |
| EP-1896412-A2 | OXINDOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2008-03-12 | — | — | EP | claimed |
| WO-2006136606-A2 | OXINDOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-28 | — | — | WO | claimed |
| US-20060293319-A1 | Oxindole derivatives | LUK KIM-CHUN | 2006-12-28 | — | — | US | claimed |
| US-20060074084-A1 | Inhibitors of soluble adenylate cyclase | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-04-06 | — | — | US | claimed |
| US-20040224992-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-11-11 | — | — | US | claimed |
| WO-2004075864-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-09-10 | — | — | WO | claimed |