Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 17/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 17/20 | 0.44 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | GRAMD1A | Q96CP6 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25336837 | 1.00 | DDB1 (0.44) | DDB1CRBNSPRGRAMD1A | |
| SCHEMBL30543640 | 1.00 | DDB1 (0.44) | DDB1CRBNSPRGRAMD1A | |
| SCHEMBL25973118 | 1.00 | DDB1 (0.44) | DDB1CRBNSPRGRAMD1A | |
| SCHEMBL25340303 | 0.89 | CRBN (0.48) | DDB1CRBN | |
| SCHEMBL25339523 | 0.89 | CRBN (0.48) | DDB1CRBN | |
| SCHEMBL30543617 | 0.89 | DDB1 (0.43) | DDB1CRBNGRAMD1A | |
| SCHEMBL25971442 | 0.89 | DDB1 (0.43) | DDB1CRBNGRAMD1A | |
| SCHEMBL30543602 | 0.89 | DDB1 (0.43) | DDB1CRBNGRAMD1A | |
| SCHEMBL25973063 | 0.89 | DDB1 (0.43) | DDB1CRBNGRAMD1A | |
| SCHEMBL25335752 | 0.88 | DDB1 (0.47) | DDB1CRBNGRAMD1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147594-A2 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |