SCHEMBL25973503

SCHEMBL25973503

COc1ccc2c(c1)C=CC1(O2)N(C)c2ccc(C(=O)c3ccccc3)cc2C1(C)C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.58
MEN1 O00255 4/20 0.58
GFER P55789 1/20 0.58
MAPT P10636 7/20 0.56
SMN1; SMN2 Q16637 5/20 0.56
GAA P10253 4/20 0.56
LMNA P02545 4/20 0.56
RECQL P46063 3/20 0.56
TDP1 Q9NUW8 3/20 0.56
THRB P10828 3/20 0.56
TSHR P16473 2/20 0.56
PLIN1 O60240 1/20 0.56
PKM P14618 1/20 0.56
PLIN5 Q00G26 1/20 0.56
ABHD5 Q8WTS1 1/20 0.56
NPSR1 Q6W5P4 3/20 0.53
ALPG P10696 1/20 0.53
TP53 P04637 1/20 0.53
ALOX15 P16050 1/20 0.53
HSD17B10 Q99714 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25973483 0.93 KMT2A (0.51) KMT2AMEN1GFERMAPTSMN1; SMN2
SCHEMBL25973247 0.92 MEN1 (0.61) KMT2AMEN1GFERMAPTSMN1; SMN2
SCHEMBL25973260 0.92 MEN1 (0.53) KMT2AMEN1GFERMAPTSMN1; SMN2
SCHEMBL25973232 0.91 MEN1 (0.67) KMT2AMEN1GFERMAPTSMN1; SMN2
SCHEMBL26781612 0.88 MEN1 (0.60) KMT2AMEN1GFERMAPTSMN1; SMN2
SCHEMBL25973201 0.87 MEN1 (0.59) KMT2AMEN1GFERMAPTSMN1; SMN2
SCHEMBL25973211 0.87 MEN1 (0.59) KMT2AMEN1GFERMAPTSMN1; SMN2
SCHEMBL25973519 0.87 MEN1 (0.59) KMT2AMEN1GFERMAPTSMN1; SMN2
SCHEMBL26780944 0.85 MEN1 (0.76) KMT2AMEN1GFERMAPTSMN1; SMN2
SCHEMBL25973644 0.84 MEN1 (0.55) KMT2AMEN1GFERMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066790-A1 Process and apparatus for locally polymerizing a starting material by dual color photopolymerization and method for volumetric printing of a shaped body XOLO GMBH (DE) 2024-02-29 US disclosed
US-20240066790-A1 Process and apparatus for locally polymerizing a starting material by dual color photopolymerization and method for volumetric printing of a shaped body XOLO GMBH (DE) 2024-02-29 US disclosed
EP-4224253-B1 PROCESS, APPARATUS AND PHOTOSWITCHABLE PHOTOINITIATORS FOR LOCALLY POLYMERIZING A STARTING MATERIAL BY DUAL COLOR PHOTOPOLYMERIZATION AND METHOD FOR VOLUMETRIC PRINTING OF A SHAPED BODY XOLO GMBH (DE) 2023-11-15 EP disclosed
EP-4224253-A2 PROCESS, APPARATUS AND PHOTOSWITCHABLE PHOTOINITIATORS FOR LOCALLY POLYMERIZING A STARTING MATERIAL BY DUAL COLOR PHOTOPOLYMERIZATION AND METHOD FOR VOLUMETRIC PRINTING OF A SHAPED BODY Xolo GmbH (DE) 2023-08-09 EP disclosed