Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 8/20 | 0.39 |
| ▸ | MTOR | P42345 | 8/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 7/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | RPTOR | Q8N122 | 7/20 | 0.32 |
| ▸ | MLST8 | Q9BVC4 | 7/20 | 0.32 |
| ▸ | RICTOR | Q6R327 | 5/20 | 0.32 |
| ▸ | MAPKAP1 | Q9BPZ7 | 5/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25342561 | 1.00 | PIK3CA (0.39) | PIK3CAMTORPIK3C3NR3C2RPTOR | |
| Oxalic Acid SCHEMBL31533513 | 0.92 | PIK3CA (0.41) | PIK3CAMTORPIK3C3NR3C2 | |
| SCHEMBL11540063 | 0.76 | — | — | |
| SCHEMBL17925825 | 0.73 | PIK3C3 (0.36) | PIK3C3 | |
| SCHEMBL23654732 | 0.71 | PIK3CA (0.41) | PIK3CAMTORPIK3C3NR3C2RPTOR | |
| SCHEMBL18989221 | 0.71 | PIK3CA (0.39) | PIK3CAMTORPIK3C3NR3C2RPTOR | |
| SCHEMBL19016597 | 0.71 | PIK3CA (0.39) | PIK3CAMTORPIK3C3NR3C2RPTOR | |
| SCHEMBL5753755 | 0.71 | MAPT (0.38) | CRBNALDH1A1 | |
| SCHEMBL25343411 | 0.71 | MAPT (0.38) | CRBNALDH1A1 | |
| SCHEMBL31436247 | 0.71 | MAPT (0.38) | CRBNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135528-A1 | HETEROALICYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SUVEN LIFE SCIENCES LIMITED (IN) | 2023-07-20 | — | — | WO | disclosed |