SCHEMBL25974685

SCHEMBL25974685

CCCN(C(=O)OC(C)(C)C)[C@@H](CC)CC(=O)OC

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA14 Q9ULX7 4/20 0.40
CA12 O43570 3/20 0.40
CA1 P00915 2/20 0.40
CA7 P43166 1/20 0.40
CA2 P00918 2/20 0.38
CPB2 Q96IY4 1/20 0.30
CTSK P43235 1/20 0.30
BIRC2 Q13490 1/20 0.30
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
NCOR2 Q9Y618 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24983946 0.81 CA14 (0.41) CA14CA12CA1CA7CA2
SCHEMBL4547485 0.81 CA14 (0.38) CA14CA12CA1CA7CA2
SCHEMBL27536080 0.79 CA14 (0.37) CA14CA12CA1CA2CTSK
SCHEMBL25411706 0.78 CA14 (0.33) CA14CA12CA1CA7CA2
SCHEMBL3469119 0.76 CA14 (0.46) CA14CA12CA1CA7CA2
SCHEMBL19457048 0.74 CA14 (0.36) CA14CA12CA1CA7HDAC1
SCHEMBL25124098 0.74 CA14 (0.39) CA14CA12CA1CA7CA2
SCHEMBL14537630 0.74 CA12 (0.41) CA14CA12CA1CA7CA2
SCHEMBL19663961 0.74 CA14 (0.40) CA14CA12CA1CA7CA2
SCHEMBL13534084 0.72 HDAC6 (0.35) CA14CA12CA1CA7CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023135528-A1 HETEROALICYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF CNS DISORDERS SUVEN LIFE SCIENCES LIMITED (IN) 2023-07-20 WO disclosed