Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 13/20 | 0.49 |
| ▸ | MTOR | P42345 | 10/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597511 | 1.00 | PIK3CA (0.49) | PIK3CAMTORPIK3R1PIK3CD | |
| SCHEMBL2597492 | 0.89 | PIK3CA (0.50) | PIK3CAMTORPIK3R1PIK3CD | |
| SCHEMBL2597491 | 0.89 | PIK3CA (0.50) | PIK3CAMTORPIK3R1PIK3CD | |
| SCHEMBL2597500 | 0.88 | MTOR (0.56) | PIK3CAMTORPIK3R1 | |
| SCHEMBL2597535 | 0.82 | PIK3CA (0.49) | PIK3CAMTORPIK3R1PIK3CD | |
| SCHEMBL2597736 | 0.82 | PIK3CA (0.49) | PIK3CAMTORPIK3R1PIK3CD | |
| SCHEMBL2597498 | 0.82 | PIK3CA (0.53) | PIK3CAMTOR | |
| SCHEMBL2597502 | 0.82 | PIK3CA (0.50) | PIK3CAMTORPIK3R1 | |
| SCHEMBL2597546 | 0.82 | PIK3CA (0.53) | PIK3CAMTOR | |
| SCHEMBL2597626 | 0.80 | MTOR (0.58) | PIK3CAMTORPIK3R1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571884-A2 | MTOR SELECTIVE KINASE INHIBITORS | Xcovery Holding Company LLC (US) | 2013-03-27 | — | — | EP | claimed |
| WO-2011146594-A2 | MTOR SELECTIVE KINASE INHIBITORS | XCOVERY HOLDING COMPANY, LLC. (US) | 2011-11-24 | — | — | WO | claimed |
| EP-2571884-A2 | MTOR SELECTIVE KINASE INHIBITORS | Xcovery Holding Company LLC (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011146594-A2 | MTOR SELECTIVE KINASE INHIBITORS | XCOVERY HOLDING COMPANY, LLC. (US) | 2011-11-24 | — | — | WO | disclosed |