Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 15/20 | 0.52 |
| ▸ | BRAF | P15056 | 14/20 | 0.52 |
| ▸ | ABL1 | P00519 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25341190 | 0.87 | RAF1 (0.56) | RAF1BRAF | |
| SCHEMBL26346268 | 0.84 | RAF1 (0.50) | RAF1BRAF | |
| SCHEMBL26342366 | 0.79 | RAF1 (0.66) | RAF1BRAF | |
| SCHEMBL26342390 | 0.79 | RAF1 (0.66) | RAF1BRAF | |
| SCHEMBL26342413 | 0.79 | RAF1 (0.62) | RAF1BRAF | |
| SCHEMBL26342291 | 0.77 | RAF1 (0.63) | RAF1BRAF | |
| SCHEMBL26342452 | 0.76 | RAF1 (0.64) | RAF1BRAF | |
| SCHEMBL26342311 | 0.76 | RAF1 (0.62) | RAF1BRAF | |
| SCHEMBL26342114 | 0.76 | RAF1 (0.60) | RAF1BRAF | |
| SCHEMBL26342229 | 0.73 | RAF1 (0.59) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150681-A1 | INHIBITORS OF RAF KINASES | KINNATE BIOPHARMA INC. (US) | 2023-08-10 | — | — | WO | disclosed |