SCHEMBL25975693

SCHEMBL25975693

c1ccc(-c2nc(-c3ccc4ccccc4c3)nc(-c3cc(-c4ccc(N(c5ccccc5)c5ccc6ccccc6c5)cc4)cc4oc5ccccc5c34)n2)cc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
POLB P06746 2/20 0.31
MAPT P10636 2/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.31
CCR4 P51679 1/20 0.31
CCNC P24863 1/20 0.30
CDK8 P49336 1/20 0.30
NR1H4 Q96RI1 1/20 0.30
TERT O14746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24255398 0.99 KDM4E (0.33) KMT2AKDM4EALDH1A1MEN1TP53
SCHEMBL24066214 0.97 KDM4E (0.36) KMT2AKDM4EALDH1A1MEN1TP53
SCHEMBL26571728 0.97 KDM4E (0.36) KMT2AKDM4EALDH1A1MEN1TP53
SCHEMBL26415472 0.96 MAPT (0.32) KMT2AKDM4EALDH1A1MEN1TP53
SCHEMBL26415475 0.95 MAPT (0.32) KMT2AKDM4EALDH1A1MEN1TP53
SCHEMBL24255391 0.93 MAPT (0.35) KMT2AKDM4EALDH1A1MEN1CYP1A2
SCHEMBL24255397 0.93 MAPT (0.35) KMT2AKDM4EALDH1A1MEN1CYP1A2
SCHEMBL26415417 0.93 MAPT (0.35) KMT2AKDM4EALDH1A1MEN1CYP1A2
SCHEMBL24255440 0.92 CYP1A1 (0.36) KMT2AKDM4EALDH1A1MEN1TP53
SCHEMBL24066124 0.92 KDM4E (0.36) KMT2AKDM4EALDH1A1MEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023149718-A1 ORGANIC LIGHT-EMITTING ELEMENT INCLUDING HETEROCYCLIC COMPOUND, COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING ELEMENT, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING ELEMENT 엘티소재주식회사 2023-08-10 WO disclosed