SCHEMBL25975772

SCHEMBL25975772

c1ccc(-c2ccc(-c3nc(-c4cc(-c5ccc(N(c6ccccc6)c6ccccc6)cc5)cc5oc6ccccc6c45)nc4ccccc34)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ATM Q13315 1/20 0.41
NUDT1 P36639 2/20 0.37
PDK1 Q15118 1/20 0.36
ADORA2A P29274 1/20 0.34
WHR1 P49842 1/20 0.34
KDM1A O60341 1/20 0.33
PDE5A O76074 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
GLA P06280 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25666451 1.00 MEN1 (0.41) MEN1KMT2AATMNUDT1PDK1
SCHEMBL26415489 0.95 MEN1 (0.37) MEN1KMT2AATMNUDT1PDK1
SCHEMBL25666441 0.94 MEN1 (0.41) MEN1KMT2AATMNUDT1PDK1
SCHEMBL23312399 0.92 MEN1 (0.47) MEN1KMT2AATMNUDT1ADORA2A
SCHEMBL27391313 0.91 MEN1 (0.45) MEN1KMT2AATMNUDT1ADORA2A
SCHEMBL24255389 0.90 MEN1 (0.40) MEN1KMT2AATMNUDT1ADORA2A
SCHEMBL25975623 0.88 MEN1 (0.40) MEN1KMT2AATMNUDT1PDK1
SCHEMBL24255397 0.88 MAPT (0.35) MEN1KMT2AATMADORA2AKDM1A
SCHEMBL24585653 0.88 MEN1 (0.42) MEN1KMT2AATMNUDT1ADORA2A
SCHEMBL24255391 0.88 MAPT (0.35) MEN1KMT2AATMADORA2AKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023149718-A1 ORGANIC LIGHT-EMITTING ELEMENT INCLUDING HETEROCYCLIC COMPOUND, COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING ELEMENT, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING ELEMENT 엘티소재주식회사 2023-08-10 WO disclosed