SCHEMBL25975915

SCHEMBL25975915

c1ccc(-c2ccc3c(c2)oc2cccc(-c4nc(-c5ccccc5)c5sc6ccccc6c5n4)c23)cc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 1/20 0.38
LIMK1 P53667 6/20 0.35
ALOX5 P09917 1/20 0.33
PIM1 P11309 2/20 0.32
PIM2 Q9P1W9 2/20 0.32
PIM3 Q86V86 1/20 0.32
TNKS O95271 2/20 0.32
TNKS2 Q9H2K2 2/20 0.32
ESR2 Q92731 1/20 0.31
F9 P00740 1/20 0.31
PIK3CA P42336 1/20 0.30
PI4KA P42356 1/20 0.30
PI4KB Q9UBF8 1/20 0.30
HCRTR1 O43613 1/20 0.30
LIMK2 P53671 1/20 0.30
MMP12 P39900 1/20 0.30
MMP13 P45452 1/20 0.30
GLA P06280 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25972346 1.00 PRKDC (0.38) PRKDCLIMK1ALOX5PIM1PIM2
SCHEMBL25972348 0.98 PRKDC (0.36) PRKDCLIMK1ALOX5PIM1PIM2
SCHEMBL25972508 0.97 PRKDC (0.36) PRKDCLIMK1ALOX5PIM1PIM2
SCHEMBL22329227 0.97 PRKDC (0.36) PRKDCLIMK1ALOX5PIM1PIM2
SCHEMBL22329652 0.97 PRKDC (0.36) PRKDCLIMK1ALOX5PIM1PIM2
SCHEMBL25972470 0.97 PRKDC (0.36) PRKDCLIMK1ALOX5PIM1PIM2
SCHEMBL22195832 0.97 PRKDC (0.36) PRKDCLIMK1ALOX5PIM1PIM2
SCHEMBL25972341 0.97 PRKDC (0.36) PRKDCLIMK1ALOX5PIM1PIM2
SCHEMBL25017121 0.96 PRKDC (0.35) PRKDCLIMK1ALOX5PIM1PIM2
SCHEMBL22195587 0.96 PRKDC (0.35) PRKDCLIMK1ALOX5PIM1PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023149718-A1 ORGANIC LIGHT-EMITTING ELEMENT INCLUDING HETEROCYCLIC COMPOUND, COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING ELEMENT, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING ELEMENT 엘티소재주식회사 2023-08-10 WO disclosed