SCHEMBL2597703

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL405386	0.84	TSHR (0.47)	PARP1MEN1KMT2AMAPTPOLB
	SCHEMBL29742161	0.84	TSHR (0.47)	PARP1MEN1KMT2AMAPTPOLB
	SCHEMBL27747270	0.83	PARP1 (0.50)	PARP1MEN1KMT2AMAPTTDP1
	SCHEMBL28027642	0.82	MEN1 (0.38)	PARP1MEN1KMT2AMAPTNCOA1
	SCHEMBL8195276	0.82	MEN1 (0.38)	PARP1MEN1KMT2AMAPTNCOA1
	SCHEMBL2244805	0.82	TDP1 (0.45)	PARP1MEN1KMT2AMAPTNCOA1
	SCHEMBL12182655	0.82	PARP1 (0.40)	PARP1MEN1KMT2AMAPTNCOA1
	SCHEMBL358123	0.82	EGFR (0.42)	MEN1KMT2AMAPTNCOA1NCOA3
	SCHEMBL1024702	0.82	MAPT (0.47)	PARP1MEN1KMT2AMAPTNCOA1
	SCHEMBL21050688	0.79	MAPT (0.37)	MEN1KMT2AMAPTTSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.