Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6597868 | 0.76 | KMT2A (0.44) | NPSR1ALDH1A1ARMEN1KMT2A | |
| SCHEMBL15957683 | 0.75 | AR (0.50) | TSHRTDP1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL30503599 | 0.75 | TDP1 (0.71) | TSHRTDP1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL9719281 | 0.75 | TDP1 (0.71) | TSHRTDP1SMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL27847552 | 0.74 | TDP1 (0.46) | TDP1NPSR1L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL22655351 | 0.74 | NPSR1 (0.43) | TSHRNPSR1MAPK1RAB9ACASP6 | |
| SCHEMBL15957893 | 0.73 | TDP1 (0.44) | TSHRTDP1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL8482488 | 0.73 | TSHR (0.46) | TSHRTDP1NPSR1POLBL3MBTL1 | |
| SCHEMBL626732 | 0.73 | GRIN2D (0.35) | TSHRTDP1NPSR1POLBL3MBTL1 | |
| SCHEMBL15957703 | 0.72 | TDP1 (0.43) | TSHRTDP1SMN1; SMN2MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011145022-A1 | 2-PHENYL BENZOYLAMIDES | PFIZER INC. (US) | 2011-11-24 | — | — | WO | disclosed |