Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 7/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24454734 | 1.00 | MIF (0.37) | MIFHDAC6PRKCATSHRALDH1A1 | |
| SCHEMBL3070099 | 0.90 | — | — | |
| SCHEMBL28619795 | 0.90 | — | — | |
| SCHEMBL24454457 | 0.85 | MIF (0.37) | MIFHDAC6PRKCATSHRALDH1A1 | |
| SCHEMBL24454692 | 0.83 | MIF (0.36) | MIFHDAC6PRKCATSHRALDH1A1 | |
| SCHEMBL9724891 | 0.77 | MIF (0.37) | MIFHDAC6PRKCATSHRBRD4 | |
| SCHEMBL14454532 | 0.76 | MIF (0.36) | MIFHDAC6PRKCATSHRBRD4 | |
| SCHEMBL8436542 | 0.76 | CHRM2 (0.43) | MIFHDAC6TSHRALDH1A1BRD4 | |
| SCHEMBL8065510 | 0.76 | CHRM2 (0.43) | MIFHDAC6TSHRALDH1A1BRD4 | |
| SCHEMBL321971 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4227308-A1 | TETRAHYDROBENZOFURODIAZEPINONE COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | Japan Tobacco Inc. (JP) | 2023-08-16 | — | — | EP | disclosed |