⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25977967 | 0.88 | — | — | |
| SCHEMBL25507845 | 0.87 | — | — | |
| SCHEMBL25977948 | 0.74 | — | — | |
| SCHEMBL19569855 | 0.73 | — | — | |
| SCHEMBL25500716 | 0.72 | — | — | |
| SCHEMBL22922371 | 0.69 | — | — | |
| SCHEMBL20000779 | 0.69 | — | — | |
| SCHEMBL23265113 | 0.69 | TSHR (0.31) | — | |
| SCHEMBL25130081 | 0.68 | — | — | |
| SCHEMBL25978120 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250091-A1 | ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. | 2023-08-10 | — | — | US | disclosed |