Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7507650 | 0.90 | EPHX1 (0.65) | HTTPOLBEPHX1ALDH1A1KDM4E | |
| SCHEMBL12974617 | 0.86 | EPHX1 (0.60) | HTTPOLBEPHX1ALDH1A1KDM4E | |
| SCHEMBL13122989 | 0.85 | HTT (0.67) | HTTPOLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7514779 | 0.84 | EPHX1 (0.61) | HTTPOLBEPHX1ALDH1A1KDM4E | |
| SCHEMBL24381846 | 0.83 | POLB (0.65) | HTTPOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3766614 | 0.83 | POLB (0.61) | HTTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2275794 | 0.83 | POLB (0.68) | HTTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11051077 | 0.83 | EPHX1 (0.70) | HTTPOLBEPHX1ALDH1A1KDM4E | |
| SCHEMBL11262889 | 0.82 | MEN1 (0.46) | HTTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL10551696 | 0.82 | EPHX1 (0.63) | HTTEPHX1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571871-B1 | Process for the preparation of chiral triazolones | SANDOZ AG (CH) | 2017-06-21 | — | — | EP | claimed |
| EP-2571847-B1 | PROCESS FOR THE PREPARATION OF CHIRAL HYDRAZIDES | SANDOZ AG (CH) | 2016-09-21 | — | — | EP | claimed |
| US-20130210833-A1 | PROCESS FOR THE PREPARATION OF CHIRAL TRIAZOLONES | SANDOZ AG (CH) | 2013-08-15 | — | — | US | claimed |
| US-20130203993-A1 | PROCESS FOR THE PREPARATION OF CHIRAL HYDRAZIDES | SANDOZ AG (CH) | 2013-08-08 | — | — | US | claimed |
| EP-2571871-A1 | PROCESS FOR THE PREPARATION OF CHIRAL TRIAZOLONES | Sandoz AG (CH) | 2013-03-27 | — | — | EP | claimed |
| EP-2571847-A1 | PROCESS FOR THE PREPARATION OF CHIRAL HYDRAZIDES | Sandoz AG (CH) | 2013-03-27 | — | — | EP | claimed |
| CN-102906087-A | Process for the preparation of chiral triazolones | SANDOZ AG | 2013-01-30 | — | — | CN | claimed |
| CN-102892750-A | Process for the preparation of chiral hydrazides | SANDOZ AG | 2013-01-23 | — | — | CN | claimed |
| WO-2011144653-A1 | PROCESS FOR THE PREPARATION OF CHIRAL TRIAZOLONES | SANDOZ AG (CH) | 2011-11-24 | — | — | WO | claimed |
| WO-2011144655-A1 | PROCESS FOR THE PREPARATION OF CHIRAL HYDRAZIDES | SANDOZ AG (CH) | 2011-11-24 | — | — | WO | claimed |
| EP-4683909-A2 | ATM KINASE INHIBITORS | Eberhard Karls Universität Tübingen (DE) | 2026-01-28 | — | — | EP | disclosed |
| US-20260015328-A1 | ATM KINASE INHIBITORS | EBERHARD KARLS UNIVERSITÄT TÜBINGEN (DE) | 2026-01-15 | — | — | US | disclosed |
| WO-2024194460-A2 | ATM KINASE INHIBITORS | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2024-09-26 | — | — | WO | disclosed |
| EP-4434972-A1 | ATM KINASE INHIBITORS | Eberhard-Karls-Universität Tübingen (DE) | 2024-09-25 | — | — | EP | disclosed |
| EP-2721013-B1 | PROCESS FOR THE PREPARATION OF A CHIRAL COMPOUND | SANDOZ AG (CH) | 2018-02-21 | — | — | EP | disclosed |
| WO-2012172015-A1 | PROCESS FOR THE PREPARATION OF A CHIRAL COMPOUND | SANDOZ AG (CH) | 2012-12-20 | — | — | WO | disclosed |
| WO-2011144655-A1 | PROCESS FOR THE PREPARATION OF CHIRAL HYDRAZIDES | SANDOZ AG (CH) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011144653-A1 | PROCESS FOR THE PREPARATION OF CHIRAL TRIAZOLONES | SANDOZ AG (CH) | 2011-11-24 | — | — | WO | disclosed |
| US-4352913-A | EPOXY RESIN CURING AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-10-05 | — | — | US | disclosed |
| US-4324739-A | CURING AGENTS FOR POLYEPOXIDES | CIBA-GEIGY CORPORATION (US) | 1982-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203993-A1 | PROCESS FOR THE PREPARATION OF CHIRAL HYDRAZIDES | CYP3A5, CYP51A1, CYP3A4 | HTT 2309/4885POLB 1537/4885EPHX1 1588/4885 |
| US-20130210833-A1 | PROCESS FOR THE PREPARATION OF CHIRAL TRIAZOLONES | CYP3A4, CYP3A43, CYP3A5 | HTT 4626/4885POLB 902/4885EPHX1 3365/4885 |
| US-20260015328-A1 | ATM KINASE INHIBITORS | ATM, CHEK2, CHEK1 | HTT 2555/4885POLB 151/4885EPHX1 4682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.