SCHEMBL25979768

SCHEMBL25979768

C=C/C=C(\C=C/C)Nc1nccc(/C(C=C)=C/C=C\C)n1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
KDM5A P29375 1/20 0.31
JMJD1C Q15652 1/20 0.31
KDM3A Q9Y4C1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27444918 0.94 KDM4E (0.33) KDM4EKDM5AJMJD1CKDM3A
SCHEMBL25979740 0.91 KDM4E (0.33) KDM4EKDM5AJMJD1CKDM3A
SCHEMBL25979776 0.86
SCHEMBL25979937 0.80
SCHEMBL14871555 0.73 SYK (0.33)
SCHEMBL21376380 0.73
SCHEMBL18401109 0.73
SCHEMBL21376382 0.70
SCHEMBL27445951 0.70 KDM4E (0.31) KDM4EKDM5AJMJD1CKDM3A
SCHEMBL27446046 0.67 AURKA (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023150197-A1 ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF NEXYS THERAPEUTICS, INC. (US) 2023-08-10 WO disclosed