Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 8/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1444762 | 0.85 | MKNK1 (0.44) | MIFKMOMKNK1MKNK2 | |
| SCHEMBL2598758 | 0.71 | MIF (0.38) | MIF | |
| SCHEMBL1444763 | 0.69 | MIF (0.65) | MIFKMO | |
| SCHEMBL14804510 | 0.69 | MIF (0.42) | MIFKMO | |
| SCHEMBL1445810 | 0.68 | MIF (0.57) | MIFKMO | |
| SCHEMBL1445299 | 0.67 | MIF (0.56) | MIFKMOMKNK1MKNK2 | |
| SCHEMBL20813389 | 0.64 | MIF (0.68) | MIFKMO | |
| SCHEMBL14804511 | 0.63 | MIF (0.40) | MIF | |
| SCHEMBL14818901 | 0.63 | MIF (0.40) | MIF | |
| SCHEMBL17547132 | 0.63 | MKNK1 (0.47) | MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011146824-A1 | METHODS AND COMPOSITIONS FOR MODULATING OCULAR DAMAGE | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2011-11-24 | — | — | WO | disclosed |