Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ROS1 | P08922 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25991704 | 0.93 | AKR1B1 (0.37) | CNR2AKR1B1KLKB1KLK1KCNH2 | |
| SCHEMBL25991409 | 0.93 | KLKB1 (0.39) | CNR2AKR1B1KLKB1KLK1KCNH2 | |
| SCHEMBL25992229 | 0.92 | AKR1B1 (0.39) | CNR2AKR1B1KLKB1KLK1KCNH2 | |
| SCHEMBL25991673 | 0.92 | AKR1B1 (0.38) | CNR2AKR1B1KLKB1KLK1KCNH2 | |
| SCHEMBL25992162 | 0.92 | AKR1B1 (0.36) | CNR2AKR1B1KLKB1KLK1KCNH2 | |
| SCHEMBL25992264 | 0.92 | ROS1 (0.38) | CNR2AKR1B1KLKB1KLK1KCNH2 | |
| SCHEMBL25991878 | 0.92 | AKR1B1 (0.37) | CNR2AKR1B1KLKB1KLK1KCNH2 | |
| SCHEMBL25992231 | 0.92 | AKR1B1 (0.37) | CNR2AKR1B1KLKB1KLK1KCNH2 | |
| SCHEMBL25991692 | 0.92 | AKR1B1 (0.37) | CNR2AKR1B1KLKB1KLK1KCNH2 | |
| SCHEMBL25991844 | 0.91 | CNR2 (0.37) | CNR2AKR1B1KLKB1KLK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154905-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-08-17 | — | — | WO | disclosed |