⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791253 | 1.00 | — | — | |
| SCHEMBL17164603 | 1.00 | CYP1A2 (0.55) | — | |
| SCHEMBL105210 | 1.00 | — | — | |
| SCHEMBL105145 | 0.97 | CYP1A2 (0.52) | — | |
| Ammonia Solution, Strong SCHEMBL20582897 | 0.97 | TDP1 (0.55) | — | |
| SCHEMBL6737976 | 0.97 | CYP1A2 (0.52) | — | |
| SCHEMBL10884759 | 0.97 | CYP1A2 (0.52) | — | |
| Hydrochloric Acid SCHEMBL8052774 | 0.97 | CYP1A2 (0.52) | — | |
| SCHEMBL106819 | 0.97 | CYP1A2 (0.52) | — | |
| Ethane SCHEMBL5873454 | 0.97 | CYP1A2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336887-B | Benzimidazole chiral heterocyclic compound and preparation method and application thereof | 中山大学 | 2021-12-17 | — | — | CN | claimed |
| CN-109336887-A | A kind of benzimidazole and chiral heterocycle class compound and its preparation method and application | 中山大学 | 2019-02-15 | — | — | CN | claimed |
| CN-104610363-B | Phosphorous amide ligand and its preparation method and application | 中山大学 | 2018-04-10 | — | — | CN | claimed |
| CN-106831862-A | Axial chirality monophosphorus ligand of one class chirality bridging and preparation method thereof | 中山大学 | 2017-06-13 | — | — | CN | claimed |
| CN-102875601-B | Phosphine-oxazoline ligand and ionic type metal title complex thereof and its enantiomorph or raceme preparation method and application | SUN YAT-SEN UNIVERSITY (CN) | 2016-03-09 | — | — | CN | claimed |
| CN-102532196-B | Phosphine ligands and enantiomorph or raceme and preparation method thereof | SUN YAT-SEN UNIVERSITY (CN) | 2015-09-02 | — | — | CN | claimed |
| CN-104610363-A | Phosphoramidite ligand as well as preparation method and application thereof | UNIV SUN YAT SEN | 2015-05-13 | — | — | CN | claimed |
| CN-102875601-A | Preparation method and application for phosphine-oxazoline ligand, and ionic metal complex, enantiomer or racemate thereof | UNIV SUN YAT SEN | 2013-01-16 | — | — | CN | claimed |
| EP-1504002-B1 | METHOD FOR THE PRODUCTION OF OPTICALLY ACTIVE BETA-AMINOKETONES AND OPTICALLY ACTIVE 1,3-AMINOALCOHOLS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2012-12-19 | — | — | EP | claimed |
| CN-102532196-A | Phosphine ligand and enantiomer or racemic body thereof and preparation methods thereof | UNIV SUN YAT SEN | 2012-07-04 | — | — | CN | claimed |
| CN-102516300-A | Phosphine ligands, enantiomers or racemates thereof, and preparation methods of above | UNIV SUN YAT SEN | 2012-06-27 | — | — | CN | claimed |
| WO-2011145019-A1 | IMPROVED PROCESS FOR DIPHENYLPROPYLAMINE DERIVATIVES | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2011-11-24 | — | — | WO | claimed |
| US-7161008-B2 | Optically active β-aminoketones, optically active 1,3-amino alcohols and processes for preparing them | Sanofi - Aventis Deutschland GmbH (DE) | 2007-01-09 | — | — | US | claimed |
| US-20040030145-A1 | Optically active B-aminoketones, optically active 1,3-amino alcohols and processes for preparing them | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-02-12 | — | — | US | claimed |
| EP-0481712-B1 | Process for production of optically active methylsuccinic acid | NIPPON OIL CO LTD (JP) | 1996-04-24 | — | — | EP | claimed |
| US-5217887-A | PROCESS FOR PRODUCTION OF (R) METHYLSUCCINIC ACID FROM SQUALENE USING CANDIDA LIPOLYTICA | NIPPON OIL CO., LTD. (JP) | 1993-06-08 | — | — | US | claimed |
| US-4061657-A | Process for preparing a 2(R) or 2(S) tricyclic lactone glycol | THE UPJOHN COMPANY (US) | 1977-12-06 | — | — | US | claimed |
| US-4048193-A | Process for bicyclic lactone dials | THE UPJOHN COMPANY (US) | 1977-09-13 | — | — | US | claimed |
| US-3953473-A | Tricyclic lactone glycol sulfonates | THE UPJOHN COMPANY (US) | 1976-04-27 | — | — | US | claimed |
| US-20250339569-A1 | CARBONIC ANHYDRASE IX LIGANDS | 3B PHARMACEUTICALS GMBH (DE) | 2025-11-06 | — | — | US | disclosed |
| CN-119842643-A | Alkene reductase mutant and application thereof in synthesis of (R) -2-methyl succinic acid dimethyl ester | 中国科学院天津工业生物技术研究所 | 2025-04-18 | — | — | CN | disclosed |
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230278953-A1 | WATER SOLUBLE PRODRUGS OF PTBA FOR USE IN HDAC INHIBITION AND ENHANCING RENAL RECOVERY FOLLOWING ACUTE KIDNEY INJURY | KLOTHO THERAPEUTICS, INC. | 2023-09-07 | — | — | US | disclosed |
| US-11535660-B1 | Modulators of G-protein coupled receptors | Cannot Therapeutics, Inc. (US) | 2022-12-27 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-111944515-B | Circular polarization luminescent material and preparation method and application thereof | 中国科学院化学研究所 | 2022-05-10 | — | — | CN | disclosed |
| US-11236122-B2 | Triterpene amine derivatives | DFH THERAPEUTICS (US) | 2022-02-01 | — | — | US | disclosed |
| CN-109336887-B | Benzimidazole chiral heterocyclic compound and preparation method and application thereof | 中山大学 | 2021-12-17 | — | — | CN | disclosed |
| US-20210289794-A1 | COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE | FLAGSHIP PIONEERING INNOVATIONS V, INC. | 2021-09-23 | — | — | US | disclosed |
| US-20210253627-A1 | TRITERPENE AMINE DERIVATIVES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2021-08-19 | — | — | US | disclosed |
| CN-112236161-A | Modulators of G protein-coupled receptors | 卡莫特治疗学股份有限公司 | 2021-01-15 | — | — | CN | disclosed |
| CN-106831862-B | Chiral bridged axial chiral monophosphine ligand and preparation method thereof | 中山大学 | 2021-01-15 | — | — | CN | disclosed |
| CN-109336887-A | A kind of benzimidazole and chiral heterocycle class compound and its preparation method and application | 中山大学 | 2019-02-15 | — | — | CN | disclosed |
| CN-104610363-B | Phosphorous amide ligand and its preparation method and application | 中山大学 | 2018-04-10 | — | — | CN | disclosed |
| CN-106831862-A | Axial chirality monophosphorus ligand of one class chirality bridging and preparation method thereof | 中山大学 | 2017-06-13 | — | — | CN | disclosed |
| US-20160271082-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-09-22 | — | — | US | disclosed |
| US-20160271081-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-09-22 | — | — | US | disclosed |
| US-20160176906-A1 | Chemical Compounds | ASTRAZENECA AB (SE) | 2016-06-23 | — | — | US | disclosed |
| US-9248140-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2016-02-02 | — | — | US | disclosed |
| US-20150328239-A1 | Chemical Compounds | ASTRAZENECA AB (SE) | 2015-11-19 | — | — | US | disclosed |
| US-20150315154-A1 | HISTIDINYLATED CATIONIC AMPHIPHILES, PROCESS FOR PREPARATION THEROF AND THEIR LIPOSOMAL FORMULATION | COUNCIL SCIENT IND RES (IN) | 2015-11-05 | — | — | US | disclosed |
| US-9145425-B2 | Cephem compound having catechol group | SHIONOGI & CO., LTD. (JP) | 2015-09-29 | — | — | US | disclosed |
| CN-102532196-B | Phosphine ligands and enantiomorph or raceme and preparation method thereof | SUN YAT-SEN UNIVERSITY (CN) | 2015-09-02 | — | — | CN | disclosed |
| US-20150197506-A1 | NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2015-07-16 | — | — | US | disclosed |
| US-20150197506-A1 | NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2015-07-16 | — | — | US | disclosed |
| US-20150197506-A1 | NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2015-07-16 | — | — | US | disclosed |
| CN-104610363-A | Phosphoramidite ligand as well as preparation method and application thereof | UNIV SUN YAT SEN | 2015-05-13 | — | — | CN | disclosed |
| US-9018244-B2 | Benzopyran compounds, compositions and uses thereof | OLEMA PHARMACEUTICALS, INC. (US) | 2015-04-28 | — | — | US | disclosed |
| US-9018244-B2 | Benzopyran compounds, compositions and uses thereof | OLEMA PHARMACEUTICALS, INC. (US) | 2015-04-28 | — | — | US | disclosed |
| US-9018381-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2015-04-28 | — | — | US | disclosed |
| US-9018244-B2 | Benzopyran compounds, compositions and uses thereof | OLEMA PHARMACEUTICALS, INC. (US) | 2015-04-28 | — | — | US | disclosed |
| CN-104169266-A | Novel benzopyran compounds, compositions and uses thereof | OLEMA PHARMACEUTICALS INC | 2014-11-26 | — | — | CN | disclosed |
| US-8883773-B2 | Cephem compound having pseudo-catechol group | SHIONOGI & CO., LTD. (JP) | 2014-11-11 | — | — | US | disclosed |
| EP-2791128-A1 | NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | Olema Pharmaceuticals, Inc. (US) | 2014-10-22 | — | — | EP | disclosed |
| US-20130310344-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ASTRAZENECA AB (UK) | 2013-11-21 | — | — | US | disclosed |
| US-20130178445-A1 | Novel Benzopyran Compounds, Compositions and Uses Thereof | OLEMA PHARMACEUTICALS, INC. (US) | 2013-07-11 | — | — | US | disclosed |
| US-20130178445-A1 | Novel Benzopyran Compounds, Compositions and Uses Thereof | OLEMA PHARMACEUTICALS, INC. (US) | 2013-07-11 | — | — | US | disclosed |
| US-20130178445-A1 | Novel Benzopyran Compounds, Compositions and Uses Thereof | OLEMA PHARMACEUTICALS, INC. (US) | 2013-07-11 | — | — | US | disclosed |
| WO-2013090921-A1 | NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2013-06-20 | — | — | WO | disclosed |
| WO-2013090921-A1 | NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2013-06-20 | — | — | WO | disclosed |
| US-20130102583-A1 | CEPHEM COMPOUND HAVING CATECHOL GROUP | SHIONOGI & CO., LTD. (JP) | 2013-04-25 | — | — | US | disclosed |
| CN-102875601-A | Preparation method and application for phosphine-oxazoline ligand, and ionic metal complex, enantiomer or racemate thereof | UNIV SUN YAT SEN | 2013-01-16 | — | — | CN | disclosed |
| CN-102532196-A | Phosphine ligand and enantiomer or racemic body thereof and preparation methods thereof | UNIV SUN YAT SEN | 2012-07-04 | — | — | CN | disclosed |
| CN-102516300-A | Phosphine ligands, enantiomers or racemates thereof, and preparation methods of above | UNIV SUN YAT SEN | 2012-06-27 | — | — | CN | disclosed |
| US-20120035134-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2012-02-09 | — | — | US | disclosed |
| WO-2011145019-A1 | IMPROVED PROCESS FOR DIPHENYLPROPYLAMINE DERIVATIVES | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2011-11-24 | — | — | WO | disclosed |
| EP-1758844-B1 | PHOSPHINE-PHOSPHORAMIDITE COMPOUNDS | JOHNSON MATTHEY PLC (GB) | 2010-12-15 | — | — | EP | disclosed |
| EP-1501819-B1 | ESTROGEN RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2010-09-15 | — | — | EP | disclosed |
| US-7512309-B2 | Polymer composition, plastic optical fiber, plastic optical fiber cable, and method for manufacturing plastic optical fiber | MITSUBISHI RAYON CO, LTD. (JP) | 2009-03-31 | — | — | US | disclosed |
| EP-1758845-B1 | PREPARATION OF AMINOPHOSPHINES | JOHNSON MATTHEY PLC (GB) | 2008-12-03 | — | — | EP | disclosed |
| US-20080166091-A1 | Polymer Composition, Plastic Optical Fiber, Plastic Optical Fiber Cable, and Method for Manufacturing Plastic Optical Fiber | MITSUBISHI RAYON CO., LTD. (JP) | 2008-07-10 | — | — | US | disclosed |
| CN-101087820-A | Polymer composition, plastic optical fiber, plastic optical cable, and method for producing plastic optical fiber | MITSUBISHI RAYON CO (JP) | 2007-12-12 | — | — | CN | disclosed |
| EP-1834968-A1 | POLYMER COMPOSITION, PLASTIC OPTICAL FIBER, PLASTIC OPTICAL FIBER CABLE AND METHOD FOR PRODUCING PLASTIC OPTICAL FIBER | Mitsubishi Rayon Co., Ltd. (JP) | 2007-09-19 | — | — | EP | disclosed |
| EP-1626949-B1 | SUPPORTED METAL-PHOSPHINE-AMINOPHOSPHINE CATALYSTS | EASTMAN CHEM CO (US) | 2007-03-21 | — | — | EP | disclosed |
| EP-1758844-A1 | PHOSPHINE-PHOSPHORAMIDITE COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2007-03-07 | — | — | EP | disclosed |
| EP-1758845-A2 | PREPARATION OF AMINOPHOSPHINES | EASTMAN CHEMICAL COMPANY (US) | 2007-03-07 | — | — | EP | disclosed |
| US-7161008-B2 | Optically active β-aminoketones, optically active 1,3-amino alcohols and processes for preparing them | Sanofi - Aventis Deutschland GmbH (DE) | 2007-01-09 | — | — | US | disclosed |
| US-7138426-B2 | Estrogen receptor modulators | MERCK & CO., INC. (US) | 2006-11-21 | — | — | US | disclosed |
| EP-1626949-A1 | SUPPORTED METAL-PHOSPHINE-AMINOPHOSPHINE CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2006-02-22 | — | — | EP | disclosed |
| WO-2006012045-A1 | PHOSPHINE-PHOSPHORAMIDITE COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2006-02-02 | — | — | WO | disclosed |
| WO-2006012046-A2 | PREPARATION OF AMINOPHOSPHINES | EASTMAN CHEMICAL COMPANY (US) | 2006-02-02 | — | — | WO | disclosed |
| US-20050234245-A1 | Estrogen receptor modulators | MERCK SHARP & DOHME CORP. | 2005-10-20 | — | — | US | disclosed |
| US-6936718-B2 | Preparation of rotamer mixtures of pharmaceutical salts | SCHERING CORPORATION (US) | 2005-08-30 | — | — | US | disclosed |
| US-20050176758-A1 | 2-(hydroxy or methoxymethoxy)-4-(carboxy or alkoxycarbonyl)-5-(fluoro or hydrogen)-7-oxabicyclo(4.1.0)hept-3-ene chemical intermediates to neuraminidase inhibitors | GILEAD SCIENCES, INC. | 2005-08-11 | — | — | US | disclosed |
| US-6906213-B1 | Preparation of aminophosphines | EASTMAN CHEMICAL COMPANY (US) | 2005-06-14 | — | — | US | disclosed |
| US-6906212-B1 | Phosphine-phosphoramidite compounds | EASTMAN CHEMICAL COMPANY (US) | 2005-06-14 | — | — | US | disclosed |
| CN-1599610-A | Preparation of pharmaceutical salts of 4((z)-(4-bromophenyl)(ethoxyimino)methyl)-1'-((2,4-dimethyl-1-oxido-3-pyridinyl)carbonyl)-4'-methyl-1,4'bipiperidine as ccr5-antagonists for the treatment of aid | SCHERING CORP (US) | 2005-03-23 | — | — | CN | disclosed |
| WO-2005019177-A1 | AMINOPIPERIDINE AMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |
| EP-1503973-A2 | HYDROGENATION IN SUPERCRITICAL C1-4 FLUORINATED HYDROCARBONS | Advanced Phytonics Limited (GB) | 2005-02-09 | — | — | EP | disclosed |
| US-20040260126-A1 | Supported metal-phosphine-aminophosphine catalysts | EASTMAN CHEMICAL COMPANY | 2004-12-23 | — | — | US | disclosed |
| WO-2004108651-A1 | SUPPORTED METAL-PHOSPHINE-AMINOPHOSPHINE CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2004-12-16 | — | — | WO | disclosed |
| EP-1448528-A2 | PREPARATION OF PHARMACEUTICAL SALTS OF 4((Z)-(4-BROMOPHENYL)(ETHOXYIMINO)METHYL)-1'-((2,4-DIMETHYL-1-OXIDO-3-PYRIDINYL)CARBONYL)-4'-METHYL-1,4'BIPIPERIDINE AS CCR5-ANTAGONISTS FOR THE TREATMENT OF AIDS AND RELATED HIV INFECTIONS | SCHERING CORPORATION (US) | 2004-08-25 | — | — | EP | disclosed |
| US-6750213-B2 | BONE DISORDERS; UROGENITAL SYSTEM DISORDERS; ANTICANCER AGENTS | MERCK & CO., INC. | 2004-06-15 | — | — | US | disclosed |
| US-20040044047-A1 | Alpha and beta-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G.D. SEARLE & CO. | 2004-03-04 | — | — | US | disclosed |
| US-20040030145-A1 | Optically active B-aminoketones, optically active 1,3-amino alcohols and processes for preparing them | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-02-12 | — | — | US | disclosed |
| US-20030225132-A1 | Heterocyclic salts such as 3-(3-Hydroxyphenyl)-2-(4-(2-(1-pyrrolidinium)ethoxyphenol)-2,3-dihydro-1,4 -benzoxathiin-6-ol hydrochloride salt, used as estrane agonists, for phrophylaxis of bone disorders | DININNO FRANK P (US) | 2003-12-04 | — | — | US | disclosed |
| WO-2003095084-A2 | HYDROGENATION IN SUPERCRITICAL C1-4 FLUORINATED HYDROCARBONS | ADVANCED PHYTONICS LIMITED (GB) | 2003-11-20 | — | — | WO | disclosed |
| CN-1125808-C | Process for preparation of dicarboxylic acid monoesters | MITSUBISHI RAYON CO (JP) | 2003-10-29 | — | — | CN | disclosed |
| WO-2003086388-A1 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-10-23 | — | — | WO | disclosed |
| WO-2003087073-A1 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-10-23 | — | — | WO | disclosed |
| WO-2003066593-A2 | PREPARATION OF PHARMACEUTICAL SALTS OF 4 ( (Z) - (4-BROMOPHENYL) (ETHOXYIMINO) METHYL )-1'-( (2,4-DIMETHYL-1-OXIDO-3-PYRIDINYL) CARBONYL) -4'-METHYL-1,4' BIPIPERIDINE AS CCR5-ANTAGONISTS FOR THE TREATMENT OF AIDS AND RELATED HIV INFECTIONS | SCHERING CORPORATION (US) | 2003-08-14 | — | — | WO | disclosed |
| US-20030139446-A1 | Preparation of pharmaceutical salts | SCHERING CORPORATION | 2003-07-24 | — | — | US | disclosed |
| US-6518438-B2 | Reacting chemical intermediate with reducing agent; neuraminidase inhibitor | GILEAD SCIENCES, INC. | 2003-02-11 | — | — | US | disclosed |
| US-20020165226-A1 | Estrogen receptor modulators | MERCK & CO., INC. | 2002-11-07 | — | — | US | disclosed |
| US-20020156300-A1 | Preparation of cyclohexene carboxylate derivatives | GILEAD SCIENCES, INC. | 2002-10-24 | — | — | US | disclosed |
| US-20020058823-A1 | Dehydrationg cyclohexylalcohol compound | GILEAD SCIENCES, INC. | 2002-05-16 | — | — | US | disclosed |
| US-6376674-B1 | BACTERICIDES; VIRICIDES | GILEAD SCIENCES, INC. | 2002-04-23 | — | — | US | disclosed |
| US-6355830-B1 | ESTER INTERCHANGE IN THE PRESENCE OF SOLVENTS A DICARBOXYLIC ACID | MITSUBISHI RAYON CO., LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| EP-0943600-B1 | PROCESSES FOR THE PREPARATION OF DICARBOXYLIC ACID MONOESTERS | MITSUBISHI RAYON CO (JP) | 2002-01-02 | — | — | EP | disclosed |
| EP-1095022-A1 | RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 2001-05-02 | — | — | EP | disclosed |
| US-6225341-B1 | FOR INHIBITING NEURAMINIDASE; FOR THERAPY AND PROPHYLAXIS OF VIRUS INFECTION | GILEAD SCIENCES, INC. | 2001-05-01 | — | — | US | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| US-6204398-B1 | USEFUL AS INTERMEDIATES THAT ARE THEMSELVES USEFUL IN THE SYNTHESIS OF NEURAMINIDASE INHIBITORS | GILEAD SCIENCES, INC. | 2001-03-20 | — | — | US | disclosed |
| US-6172082-B1 | TREATING HUMAN IMMUNODEFICIENCY VIRUS INFECTIONS | G. D. SEARLE & CO. | 2001-01-09 | — | — | US | disclosed |
| US-6057459-A | Preparation of carbocyclic compounds | GILEAD SCIENCES, INC. (US) | 2000-05-02 | — | — | US | disclosed |
| US-6034118-A | ENZYME INHIBITOR | GILEAD SCIENCES, INC. (US) | 2000-03-07 | — | — | US | disclosed |
| EP-0976734-A2 | Selective inhibitors of viral or bacterial neuraminidase | GILEAD SCIENCES, INC. (US) | 2000-02-02 | — | — | EP | disclosed |
| WO-2000002862-A1 | RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-01-20 | — | — | WO | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| CN-1237152-A | Process for producing dicarboxylic acid monoesters | MITSUBISHI RAYON CO (JP) | 1999-12-01 | — | — | CN | disclosed |
| US-5994377-A | NEURAMINIDASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 1999-11-30 | — | — | US | disclosed |
| US-5958973-A | Polyhydroxy benzoic acid derivatives and their use as neuraminidase inhibitors | GILEAD SCIENCES, INC. (US) | 1999-09-28 | — | — | US | disclosed |
| EP-0943600-A1 | PROCESSES FOR THE PREPARATION OF DICARBOXYLIC ACID MONOESTERS | Mitsubishi Rayon Co., Ltd. (JP) | 1999-09-22 | — | — | EP | disclosed |
| US-5952375-A | NEURAMINIDASE INHIBITOR FOR INHIBITION OF VIRUSES, IN PARTICULAR INFLUENZA VIRUSES; FDA ORANGE BOOK LISTED PATENT FOR OSELTAMIVIR PHOSPHATE | GILEAD SCIENCES, INC. (US) | 1999-09-14 | — | — | US | disclosed |
| US-5886213-A | CHEMICAL INTERMEDIATES USEFUL IN THE SYNTHESIS OF NEURAMINIDASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 1999-03-23 | — | — | US | disclosed |
| US-5866601-A | ACID CYCLOHEXENE DERIVATIVES, NEURAMINIDASE INHIBITORS SUCH AS OSELTAMIVIR | GILEAD SCIENCES, INC. (US) | 1999-02-02 | — | — | US | disclosed |
| US-5859284-A | Preparation of carbocyclic compounds | GILEAD SCIENCES, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| US-5811450-A | DIAGNOSIS, TREATMENT OF HIV | GILEAD SCIENCES, INC. (US) | 1998-09-22 | — | — | US | disclosed |
| US-5763483-A | NEURAMINIDASE INHIBITOR TREATING INFLUENZA VIRUS INFECTION; OSELTAMIVIR OR THE FREE ACID THEREOF; FDA ORANGE BOOK LISTED PATENT FOR OSELTAMIVIR PHOSPHATE | GILEAD SCIENCES, INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| US-5744481-A | β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 1998-04-28 | — | — | US | disclosed |
| US-5728701-A | INHIBIT PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |
| US-5705524-A | ENZYME INHIBITORS; VIRICIDES | GILEAD SCIENCES, INC. (US) | 1998-01-06 | — | — | US | disclosed |
| EP-0796247-A1 | (-)-(3R)-3-METHYL-4-(4-(4-(4-PYRIDYL)PIPERAZIN-1-YL]PHENOXY BUTYRIC ACID AS CELLULAR ADHESION INHIBITOR | ZENECA LIMITED (GB) | 1997-09-24 | — | — | EP | disclosed |
| CN-1155884-A | (-)-(3R)-methyl-4-{-4-[4-(4-pyridyl)piperazin-1-YL]phenoxy} butyric acid as cellular adhesion inhibitor | ZENECA LTD (GB) | 1997-07-30 | — | — | CN | disclosed |
| US-5652242-A | 3-METHYL-4-(4-(4-(4-PYRIDYL)PIPERAZIN-1-YL)PHENOXY)BURYIC ACID, AMIDE OR ESTER; INHIBITORS OF BINDING OF FIBRINOGEN TO GLYCOPROTEIN | ZENECA LIMITED (GB) | 1997-07-29 | — | — | US | disclosed |
| WO-1996038416-A1 | (-)-(3R)-3-METHYL-4-{4-[4-(4-PYRIDYL)PIPERAZIN-1-YL]PHENOXY} BUTYRIC ACID AS CELLULAR ADHESION INHIBITOR | ZENECA LIMITED (GB) | 1996-12-05 | — | — | WO | disclosed |
| WO-1996026933-A1 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | GILEAD SCIENCES, INC. (US) | 1996-09-06 | — | — | WO | disclosed |
| EP-0715618-A1 | HYDROXYETHYLAMINO SULPHONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-06-12 | — | — | EP | disclosed |
| WO-1996014314-A2 | THIEPANE COMPOUNDS INHIBITING AND DETECTING HIV PROTEASE | GILEAD SCIENCES, INC. (US) | 1996-05-17 | — | — | WO | disclosed |
| EP-0481712-B1 | Process for production of optically active methylsuccinic acid | NIPPON OIL CO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| EP-0558673-B1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO CO (US) | 1996-04-17 | — | — | EP | disclosed |
| US-5482947-A | ENZYME INHIBITORS FOR HIV PROTEASE INHIBITION FROM UREA OR THIOUREA COMPOUNDS | TALLEY JOHN J (US) | 1996-01-09 | — | — | US | disclosed |
| EP-0666842-A1 | HYDROXYETHYLAMINO SULFAMIC ACID DERIVATIVES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-08-16 | — | — | EP | disclosed |
| EP-0656887-A1 | HYDROXYETHYLAMINO SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-06-14 | — | — | EP | disclosed |
| WO-1994010134-A1 | HYDROXYETHYLAMINO SULFAMIC ACID DERIVATIVES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1994-05-11 | — | — | WO | disclosed |
| WO-1994004492-A1 | HYDROXYETHYLAMINO SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1994-03-03 | — | — | WO | disclosed |
| WO-1993023368-A1 | UREA-CONTAINING HYDROXYETHYLAMINE COMPOUNDS AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1993-11-25 | — | — | WO | disclosed |
| EP-0558603-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| US-5217887-A | PROCESS FOR PRODUCTION OF (R) METHYLSUCCINIC ACID FROM SQUALENE USING CANDIDA LIPOLYTICA | NIPPON OIL CO., LTD. (JP) | 1993-06-08 | — | — | US | disclosed |
| WO-1992008688-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |
| EP-0481712-A2 | Process for production of optically active methylsuccinic acid | NIPPON OIL CO. LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |
| US-4464235-A | Carrying out electromicrobial reductions | BASF AKTIENGESELLSCHAFT (DE) | 1984-08-07 | — | — | US | disclosed |
| US-4438033-A | Steroidal chiral phosphines, methods for their preparation, catalytic systems containing them and catalytic processes in which they are used | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1984-03-20 | — | — | US | disclosed |
| EP-0081149-A1 | New steroidal chiral phosphines, methods for their preparation, catalytic systems containing them and catalytic processes in which they are used | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1983-06-15 | — | — | EP | disclosed |
| US-4061657-A | Process for preparing a 2(R) or 2(S) tricyclic lactone glycol | THE UPJOHN COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
| US-4048193-A | Process for bicyclic lactone dials | THE UPJOHN COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4048193-A | Process for bicyclic lactone dials | THE UPJOHN COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-3966751-A | Oxazolidines of 4-oxo-tricyclo[5.1.02.5 ]octan-8-endo-carboxaldehyde, neopentyl glycol acetal | THE UPJOHN COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
| US-3953473-A | Tricyclic lactone glycol sulfonates | THE UPJOHN COMPANY (US) | 1976-04-27 | — | — | US | disclosed |
| US-3953473-A | Tricyclic lactone glycol sulfonates | THE UPJOHN COMPANY (US) | 1976-04-27 | — | — | US | disclosed |
| US-3946046-A | Resolution of prostaglandin intermediates by means of oxazolidines | THE UPJOHN COMPANY (US) | 1976-03-23 | — | — | US | disclosed |
| US-3879423-A | Ethers | UPJOHN CO | 1975-04-22 | — | — | US | disclosed |
| US-3873570-A | Lactones | UPJOHN CO | 1975-03-25 | — | — | US | disclosed |
| US-3818045-A | CERTAIN BICYCLIC LACTONE DIOLS | UPJOHN CO | 1974-06-18 | — | — | US | disclosed |
| US-3818045-A | CERTAIN BICYCLIC LACTONE DIOLS | UPJOHN CO | 1974-06-18 | — | — | US | disclosed |