Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1864727 | 0.82 | HRH3 (0.63) | HRH3 | |
| SCHEMBL25357192 | 0.80 | HRH3 (0.47) | HRH3DRD2DRD4DRD3KMT2A | |
| SCHEMBL31360978 | 0.77 | MCHR1 (0.46) | HRH3DRD2DRD4DRD3KMT2A | |
| SCHEMBL29550640 | 0.73 | HRH3 (0.52) | HRH3KMT2A | |
| SCHEMBL15759178 | 0.72 | CYP1A2 (0.56) | HRH3DRD2DRD4DRD3 | |
| SCHEMBL15198045 | 0.71 | CYP1A2 (0.68) | HRH3 | |
| SCHEMBL25782607 | 0.70 | HRH3 (0.55) | HRH3DRD2DRD4DRD3 | |
| SCHEMBL1535553 | 0.70 | GRM5 (0.50) | — | |
| SCHEMBL25997024 | 0.69 | HRH3 (0.45) | HRH3DRD2DRD4DRD3 | |
| SCHEMBL82422 | 0.69 | HRH3 (0.67) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219499-A1 | A CLASS OF FUSED RING COMPOUNDS, AND PREPARATION AND USE THEREOF | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |